Anti-hypertensive effects of brazilian propolis in spontaneously hypertensive rats.

Anti-hypertensive effects of brazilian propolis in spontaneously hypertensive rats. Research Abstract Details 

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Anti-hypertensive effects of brazilian propolis in spontaneously hypertensive rats. Abstract Text:

Yoko Kubota,Keizo Umegaki,Kyoko Kobayashi,Naoko Tanaka,Satomi Kagota,Kazuki Nakamura,Masaru Kunitomo,Kazumasa Shinozuka,Yoko Kubota,Keizo Umegaki,Kyoko Kobayashi,Naoko Tanaka,Satomi Kagota,Kazuki Nakamura,Masaru Kunitomo,Kazumasa Shinozuka,

SUMMARY 1. Changes in the cardiovascular parameters of Wistar-Kyoto rats (WKY) and spontaneously hypertensive rats (SHR) were examined following a 4-week diet of either Brazilian propolis or Eucommia uloides OLIVER (tochu). 2. A 4-week diet of propolis or tochu resulted in significant reductions in systolic blood pressure in SHR but had no effect on WKY. Experiments using aorta isolated from animals fed a diet of propolis or tochu revealed increased acetylcholine-induced relaxation in SHR and no change in acetylcholine-induced relaxation in WKY. Sodium nitroprusside-induced relaxation was unaffected by propolis or tochu in both animal groups. 3. These results suggest that propolis and tochu produce an antihypertensive effect that may be mediated by potentiation of acetylcholine-induced vasodilatation.

Anti-hypertensive effects of brazilian propolis in spontaneously hypertensive rats. Publishing Authors By Initials

Y Kubota,K Umegaki,K Kobayashi,N Tanaka,S Kagota,K Nakamura,M Kunitomo,K Shinozuka,Y Kubota,K Umegaki,K Kobayashi,N Tanaka,S Kagota,K Nakamura,M Kunitomo,K Shinozuka,

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Anti-hypertensive effects of brazilian propolis in spontaneously hypertensive rats. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Clinical and experimental pharmacology & physiolog

VOLUME: 31 Suppl 2

Page Numbers: S29-30

Journal Abbreviation: Clin. Exp. Pharmacol. Physiol.

ISSN: 0305-1870

DAY: 14

MONTH: Dec

YEAR: 2004

Anti-hypertensive effects of brazilian propolis in spontaneously hypertensive rats. Information

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LANGUAGE: eng

NlmUniqueID: 425076

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Grant and Affiliation Information for Anti-hypertensive effects of brazilian propolis in spontaneously hypertensive rats.

AFFILIATION: Department of Pharmacology, School of Pharmaceutical Sciences, Mukogawa Women's University, Nishinomiya, Japan.

Country: Australia

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MEDLINETA: Clin Exp Pharmacol Physiol

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