Anti-diabetic Effects of Cesium Aqua (N,N'-ethylene(salicylideneiminato)-5-sulfonato) Oxovanadium (IV) Dihydrate in Streptozotocin-induced Diabetic Rats.

Anti-diabetic Effects of Cesium Aqua (N,N'-ethylene(salicylideneiminato)-5-sulfonato) Oxovanadium (IV) Dihydrate in Streptozotocin-induced Diabetic Rats. Research Abstract Details 

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Anti-diabetic Effects of Cesium Aqua (N,N'-ethylene(salicylideneiminato)-5-sulfonato) Oxovanadium (IV) Dihydrate in Streptozotocin-induced Diabetic Rats. Abstract Text:

Ming Li,Dan Wei,Wenjun Ding,Bharat Baruah,Debbie C Crans,Ming Li,Dan Wei,Wenjun Ding,Bharat Baruah,Debbie C Crans,

The study has been designed to investigate the anti-diabetic effects of cesium aqua (N,N'-ethylene (salicylideneiminato)-5-sulfonato) oxovanadium (IV) dihydrate (VO(salen-SO(3))), an organic vanadium compound, in streptozotocin-induced diabetic rats. VO(salen-SO(3)) was orally administrated to diabetic rats at the dose of 0.3 mg/ml through drinking water for 24 days. Blood glucose level was significantly declined, and oral glucose tolerance was improved after VO(salen-SO(3)) treatment. Moreover, liver and muscle glycogen concentrations were markedly increased in VO(salen-SO(3))-treated diabetic rats. On the other hand, aspartate amino transferase and blood urea nitrogen in serum were significantly decreased after treatment with VO(salen-SO(3)). Take together, these results suggested that VO(salen-SO(3)) may be of potential value in the therapy of diabetic symptom and hyperglycemia-induced hepatic and renal dysfunction.

Anti-diabetic Effects of Cesium Aqua (N,N'-ethylene(salicylideneiminato)-5-sulfonato) Oxovanadium (IV) Dihydrate in Streptozotocin-induced Diabetic Rats. Publishing Authors By Initials

M Li,D Wei,W Ding,B Baruah,DC Crans,M Li,D Wei,W Ding,B Baruah,DC Crans,

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Anti-diabetic Effects of Cesium Aqua (N,N'-ethylene(salicylideneiminato)-5-sulfonato) Oxovanadium (IV) Dihydrate in Streptozotocin-induced Diabetic Rats. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Biological trace element research

VOLUME: 121

Page Numbers: 226-32

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ISSN: 0163-4984

DAY: 30

MONTH: 10

YEAR: 2007

Anti-diabetic Effects of Cesium Aqua (N,N'-ethylene(salicylideneiminato)-5-sulfonato) Oxovanadium (IV) Dihydrate in Streptozotocin-induced Diabetic Rats. Information

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LANGUAGE: eng

NlmUniqueID: 7911509

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AFFILIATION: College of Life Science, Graduate University of Chinese Academy of Sciences, Beijing, 100049, China.

Country: United States

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MEDLINETA: Biol Trace Elem Res

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