Anterior lumbar interbody fusion with osteoinductive growth factors.

Anterior lumbar interbody fusion with osteoinductive growth factors. Research Abstract Details 

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Anterior lumbar interbody fusion with osteoinductive growth factors. Abstract Text:

H S Sandhu,

Anterior intervertebral fusion increasingly is used as a treatment for discogenic or intersegmental pathologic diseases of the lumbar spine. This is in part attributable to the evolution and refinement of laparoscopic and minimally invasive surgical techniques that now can be used to access the anterior spinal column. It also is attributable to the availability of newer generation intervertebral fixation devices such as the threaded titanium cages or threaded allograft bone dowels, both of which are technically simpler to implant. Recently, limited clinical studies of intervertebral lumbar fusion have examined the use of these devices combined with osteoinductive growth factors as substitutes for autogenous bone graft. Early clinical results of lumbar fusion using threaded intervertebral implants filled with recombinant human bone morphogenetic protein-2 have been favorable. Higher fusion rates, shorter operative times, and shorter hospital stays have been reported in the initial series. Clinical trials involving larger cohorts with various spinal applications for osteoinductive molecules currently are in progress.

Anterior lumbar interbody fusion with osteoinductive growth factors. Publishing Authors By Initials

HS Sandhu,

For similar peptides: intercellular signaling peptides and proteins: cytokines: transforming growth factor beta research abstracts see: peptides: intercellular signaling peptides and proteins: cytokines: transforming growth factor beta research

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Anterior lumbar interbody fusion with osteoinductive growth factors. Journal Published:

PUBLICATION TYPE: Review

Journal: Clinical orthopaedics and related research

VOLUME:

Page Numbers: 56-60

Journal Abbreviation: Clin. Orthop. Relat. Res.

ISSN: 0009-921X

DAY: 19

MONTH: Feb

YEAR: 2000

Anterior lumbar interbody fusion with osteoinductive growth factors. Information

Number of References: 18

LANGUAGE: eng

NlmUniqueID: 75674

Anterior lumbar interbody fusion with osteoinductive growth factors. Keywords Mesh Terms:

KEYWORDS: Transforming Growth Factor beta

MESH TERMS: instrumentation

Chemical & Substance for Abstract: Anterior lumbar interbody fusion with osteoinductive growth factors. Information

Substance Name: Titanium

Registry Number: 7440-32-6

Grant and Affiliation Information for Anterior lumbar interbody fusion with osteoinductive growth factors.

AFFILIATION: Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY 10021, USA.

Country: UNITED STATES

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MEDLINETA: Clin Orthop Relat Res

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