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Anterior fundoplication decreases esophageal clearance in patients undergoing Heller myotomy for achalasia.

Anterior fundoplication decreases esophageal clearance in patients undergoing Heller myotomy for achalasia. Research Abstract Details 

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  • Anterior fundoplication decreases esophageal clearance in patients undergoing Heller myotomy for achalasia. Abstract Text:

    c finleyC Finley,j cliftonJ Clifton,j yeeJ Yee,r j finleyR J Finley,c finleyC Finley,j cliftonJ Clifton,j yeeJ Yee,r j finleyR J Finley,

    BACKGROUND: Anterior fundoplication (AF) following laparoscopic Heller myotomy (LHM) for achalasia may prevent esophageal leaks and gastroesophageal reflux but cause dysphagia. Our study attempts to determine the effect of AF on esophageal leaks, nuclear medicine esophageal clearance (EC), symptom frequency (SF), and Van Trappen symptom scores (SS) for dysphagia, regurgitation, and heartburn. METHODS: Between 1995 and 2004, pre- and postoperative (2-12 months) EC, SF, and SS scores were compared in 95 patients undergoing LHM for achalasia with AF (n = 71) and without (n = 24) AF. RESULTS: There were no leaks or deaths. Laparoscopic Heller myotomy decreased the frequency of postoperative dysphagia, regurgitation, and heartburn with AF (96% preoperation versus 6% postoperation, 94% versus 3%, 58% versus 6%) (p = 0.001) and without AF (100% versus 0%, 83% versus 0%, 50% versus 4%) (p = 0.001). Laparoscopic Heller myotomy improved all SS in both groups. There was no difference between postoperative dysphagia (1.38 +/- 0.64 versus 1.17 +/- 38) p = 0.06, regurgitation (1.17 +/- 51 versus 1.04 +/- 0.20) p = 0.08, and heartburn (1.29 +/- 62 versus 1.53 +/- 0.80) p = 0.185 scores between the AF and no-AF group, respectively. There is a trend toward improvement in dysphagia and regurgitation in the no-AF group. Laparoscopic Heller myotomy improved EC in the supine and upright positions in both groups of patients (p = 0.001). There was an improved mean change in EC (10 min upright) in the no-AF group versus the AF group (50.7% +/- 30.8 versus 29.7% +/- 30.2) p = 0.004. CONCLUSIONS: Laparoscopic Heller myotomy improves esophageal transit and the frequency and severity of dysphagia, heartburn, and regurgitation in a safe manner. Patients without AF show a statistically better upright EC with a trend toward improved dysphagia and regurgitation.

    Anterior fundoplication decreases esophageal clearance in patients undergoing Heller myotomy for achalasia. Publishing Authors By Initials

    c finleyC Finley,j cliftonJ Clifton,j yeeJ Yee,rj finleyRJ Finley,c finleyC Finley,j cliftonJ Clifton,j yeeJ Yee,rj finleyRJ Finley,

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    Anterior fundoplication decreases esophageal clearance in patients undergoing Heller myotomy for achalasia. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Surgical endoscopy

    VOLUME: 21

    Page Numbers: 2178-82

    Journal Abbreviation:

    ISSN: 1432-2218

    DAY: 19

    MONTH: 05

    YEAR: 2007

    Anterior fundoplication decreases esophageal clearance in patients undergoing Heller myotomy for achalasia. Information

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    LANGUAGE: eng

    NlmUniqueID: 8806653

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    Grant and Affiliation Information for Anterior fundoplication decreases esophageal clearance in patients undergoing Heller myotomy for achalasia.

    AFFILIATION: Department of Surgery, University of British Columbia, 910 W. 10th Avenue, Room 3100, V5Z 4E3, Vancouver, British Columbia, Canada.

    Country: Germany

    Germany Research PublicationGermany Research Publication

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    MEDLINETA: Surg Endosc

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