Anterior cruciate ligament injury is determined by two variables: the ultimate failure load of the ligament and the mechanical load applied to the ligament. All factors that contribute to anterior cruciate ligament injury must do so by affecting one or both of these two basic variables. Some factors, such as sex hormones and tissue remodeling, have a multifaceted effect on the failure load of the anterior cruciate ligament and the magnitude of the load applied to it. The model also illustrates the potentially profound effects that sex hormones and tissue remodeling likely have on female susceptibility to anterior cruciate ligament injuries.
Anterior cruciate ligament biology and its relationship to injury forces. Publishing Authors By Initials
Anterior cruciate ligament biology and its relationship to injury forces. Journal Published:
PUBLICATION TYPE: Review
Journal: The Orthopedic clinics of North America
VOLUME: 37
Page Numbers: 585-91
Journal Abbreviation: Orthop. Clin. North Am.
ISSN: 0030-5898
DAY: 3
MONTH: Oct
YEAR: 2006
Anterior cruciate ligament biology and its relationship to injury forces. Information
Number of References: 62
LANGUAGE: eng
NlmUniqueID: 254463
Anterior cruciate ligament biology and its relationship to injury forces. Keywords Mesh Terms:
KEYWORDS: Tissue Inhibitor of Metalloproteinases
MESH TERMS: physiology
Chemical & Substance for Abstract: Anterior cruciate ligament biology and its relationship to injury forces. Information
Substance Name: Matrix Metalloproteinases
Registry Number: EC 3.4.24.-
Grant and Affiliation Information for Anterior cruciate ligament biology and its relationship to injury forces.
AFFILIATION: Department of Orthopaedics and Rehabilitation, University of Vermont College of Medicine, 95 Carrigan Drive, Stafford Hall, Burlington, VT 05405, USA.
Country: United States
AGENCY: United States NIAMS
GRANT: AR-049767
ACRONYM: AR
MEDLINETA: Orthop Clin North Am
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