The Notch signaling pathway patterns the developing nephron along the proximal-distal axis during renal development. In an adult acute tubular necrosis model, Kobayashi et al. now show expression of many Notch components and the activation of Notch target genes, suggesting a critical function for Notch in regenerating proximal tubules.Kidney International (2008) 73, 1207-1209. doi:10.1038/ki.2008.39.
Another niche for Notch. Publishing Authors By Initials