Anatomic consequences of intrinsic tongue muscle activation.

Anatomic consequences of intrinsic tongue muscle activation. Research Abstract Details 

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Anatomic consequences of intrinsic tongue muscle activation. Abstract Text:

E Fiona Bailey,Yu-Hsien Huang,Ralph F Fregosi,

We recently showed respiratory-related coactivation of both extrinsic and intrinsic tongue muscles in the rat. Here, we test the hypothesis that intrinsic tongue muscles contribute importantly to changes in velopharyngeal airway volume. Spontaneously breathing anesthetized rats were placed in a MRI scanner. A catheter was placed in the hypopharynx and connected to a pressure source. Axial and sagittal images of the velopharyngeal airway were obtained, and the volume of each image was computed at airway pressures ranging from +5.0 to -5.0 cm H2O. We obtained images in the hypoglossal intact animal (i.e., coactivation of intrinsic and extrinsic tongue muscles) and after selective denervation of the intrinsic tongue muscles, with and without electrical stimulation. Denervation of the intrinsic tongue muscles reduced velopharyngeal airway volume at atmospheric and positive airway pressures. Electrical stimulation of the intact hypoglossal nerve increased velopharyngeal airway volume; however, when stimulation was repeated after selective denervation of the intrinsic tongue muscles, the increase in velopharyngeal airway volume was significantly attenuated. These findings support our working hypothesis that intrinsic tongue muscles play a critical role in modulating upper airway patency.

Anatomic consequences of intrinsic tongue muscle activation. Publishing Authors By Initials

EF Bailey,YH Huang,RF Fregosi,

For similar stomatognathic diseases: mouth diseases: mouth abnormalities: velopharyngeal insufficiency research abstracts see: stomatognathic diseases: mouth diseases: mouth abnormalities: velopharyngeal insufficiency research

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Anatomic consequences of intrinsic tongue muscle activation. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Journal of applied physiology (Bethesda, Md. : 198

VOLUME: 101

Page Numbers: 1377-85

Journal Abbreviation: J. Appl. Physiol.

ISSN: 8750-7587

DAY: 6

MONTH: 07

YEAR: 2006

Anatomic consequences of intrinsic tongue muscle activation. Information

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LANGUAGE: eng

NlmUniqueID: 8502536

Anatomic consequences of intrinsic tongue muscle activation. Keywords Mesh Terms:

KEYWORDS: Velopharyngeal Insufficiency

MESH TERMS: physiopathology

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Grant and Affiliation Information for Anatomic consequences of intrinsic tongue muscle activation.

AFFILIATION: Department of Physiology, College of Medicine, The University of Arizona, Tucson, AZ 85721-0093, USA. ebailey@u.arizona.edu

Country: United States

AGENCY: United States NHLBI

GRANT: HL-56876

ACRONYM: HL

MEDLINETA: J Appl Physiol

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