OBJECTIVE: To investigate the difference of poly-genes expression between control and gut ischemia-reperfusion rats. METHODS: One thousand one hundred and seventy-six known genes expression in the liver was investigated by means of the cDNA microarray technology to reveal the differential expression genes between control and gut ischemia-reperfusion rats. RESULTS: The analysis data of the cDNA microarray showed that there were 111 genes expression changed over 5 times including 64 genes upregulated and 47 genes downregulated, some of which had not been reported to associated with gut ischemia-reperfusion injury. CONCLUSION: There are many structural and functional genes expression changed in liver of gut ischemia-reperfusion rats, which might be involved in the initiation and the development of SIRS and MODS.
[Analysis of the poly-genes expression changes in liver by gene expression profile chip in gut ischemia-reperfusion rats] Publishing Authors By Initials
[Analysis of the poly-genes expression changes in liver by gene expression profile chip in gut ischemia-reperfusion rats] Journal Published:
PUBLICATION TYPE: Research Support, Non-U.S. Gov
Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese cr
VOLUME: 15
Page Numbers: 84-7
Journal Abbreviation:
ISSN: 1003-0603
DAY: 14
MONTH: Feb
YEAR: 2003
[Analysis of the poly-genes expression changes in liver by gene expression profile chip in gut ischemia-reperfusion rats] Information
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LANGUAGE: chi
NlmUniqueID: 9887521
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AFFILIATION: Research Department of Burn Institute, 304th Hospital of People's Liberation Army, Beijing 100037, China.
Country: China
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MEDLINETA: Zhongguo Wei Zhong Bing Ji Jiu
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