With the development of genomics and the accomplishments of human genomic sequencing, polymorphic markers and their analytic approaches are more and more important, and much attention has been paid to the fact that the analysis of single nucleotide polymorphisms utilizing matrix-assisted laser desorption/ionization time-of-flight mass spectrometry(MALDI-TOF MS) is a high-throughput approach. MALDI-TOF MS can also mini-sequence and genotype short tandem repeat. The approaches to analyzing single nucleotide polymorphisms are primer oligonucleotide base extension, ligase reaction, peptide nucleotide acid, invader assay, and so on.
[Analysis of polymorphic markers by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry] Publishing Authors By Initials
[Analysis of polymorphic markers by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry] Journal Published:
PUBLICATION TYPE: Research Support, Non-U.S. Gov
Journal: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yix
VOLUME: 22
Page Numbers: 185-8
Journal Abbreviation: Zhonghua Yi Xue Yi Chuan Xue Z
ISSN: 1003-9406
DAY: 28
MONTH: Apr
YEAR: 2005
[Analysis of polymorphic markers by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry] Information
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LANGUAGE: chi
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Grant and Affiliation Information for [Analysis of polymorphic markers by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry]
AFFILIATION: School of Preclinical and Forensic Medicine, Sichuan University, Chengdu, Sichuan, 610041 P. R. China.
Country: China
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MEDLINETA: Zhonghua Yi Xue Yi Chuan Xue Z
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