The rates of metabolism of Sudan I and II and Para Red by human intestinal microflora were high compared to those of Sudan III and IV under anaerobic conditions. Metabolites of the dyes were identified as aniline, 2,4-dimethylaniline, o-toluidine, and 4-nitroaniline through high-performance liquid chromatography and liquid chromatography electrospray ionization tandem mass spectrometry analyses. These data indicate that human intestinal bacteria are able to reduce Sudan dyes to form potentially carcinogenic aromatic amines.
Anaerobic metabolism of 1-amino-2-naphthol-based azo dyes (Sudan dyes) by human intestinal microflora. Publishing Authors By Initials
Anaerobic metabolism of 1-amino-2-naphthol-based azo dyes (Sudan dyes) by human intestinal microflora. Journal Published:
PUBLICATION TYPE: Journal Article
Journal: Applied and environmental microbiology
VOLUME: 73
Page Numbers: 7759-62
Journal Abbreviation: Appl. Environ. Microbiol.
ISSN: 0099-2240
DAY: 12
MONTH: 10
YEAR: 2007
Anaerobic metabolism of 1-amino-2-naphthol-based azo dyes (Sudan dyes) by human intestinal microflora. Information
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LANGUAGE: eng
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Grant and Affiliation Information for Anaerobic metabolism of 1-amino-2-naphthol-based azo dyes (Sudan dyes) by human intestinal microflora.
AFFILIATION: Division of Microbiology, National Center for Toxicological Research, U.S. FDA, 3900 NCTR Rd., Jefferson, AR 72079-9502. huizhong.chen@fda.hhs.gov.
Country: United States
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MEDLINETA: Appl Environ Microbiol
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