An ultra acid stable reversed stationary phase.

An ultra acid stable reversed stationary phase. Research Abstract Details 

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An ultra acid stable reversed stationary phase. Abstract Text:

Brian C Trammell,Lianjia Ma,Hao Luo,Marc A Hillmyer,Peter W Carr,

We report a new reversed phase liquid chromatography (RPLC) phase with remarkable acid stability using dimethyl(ethylphenylchloromethyl)chlorosilane (1), oligomeric polystyrene (PS), and octylbenzene (C8). This phase Si-1-PS-C8 was prepared using silica modification processes and Friedel-Crafts alkylation chemistry. Under highly aggressive mobile phase conditions, Si-1-PS-C8 exhibited remarkable stability as evinced by only minimal reduction in retention factor (k') after 1400 column volumes at pH = 0.5 and 150 degrees C. The peak shapes for a variety of basic solutes were symmetric using Si-1-PS-C8. Evidence for a highly cross-linked coating of the silica particles was observed using scanning electron microscopy. The remarkable stability of this phase is unparalleled as compared to all other RPLC phases reported to date.

An ultra acid stable reversed stationary phase. Publishing Authors By Initials

BC Trammell,L Ma,H Luo,MA Hillmyer,PW Carr,

For similar inorganic chemicals: minerals: silicon dioxide research abstracts see: inorganic chemicals: minerals: silicon dioxide research

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An ultra acid stable reversed stationary phase. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Journal of the American Chemical Society

VOLUME: 125

Page Numbers: 10504-5

Journal Abbreviation: J. Am. Chem. Soc.

ISSN: 0002-7863

DAY: 3

MONTH: Sep

YEAR: 2003

An ultra acid stable reversed stationary phase. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7503056

An ultra acid stable reversed stationary phase. Keywords Mesh Terms:

KEYWORDS: Silicon Dioxide

MESH TERMS: chemistry

Chemical & Substance for Abstract: An ultra acid stable reversed stationary phase. Information

Substance Name: Silicon Dioxide

Registry Number: 7631-86-9

Grant and Affiliation Information for An ultra acid stable reversed stationary phase.

AFFILIATION: Department of Chemistry, University of Minnesota, 207 Pleasant Street SE, Minneapolis, MN 55455-0431, USA.

Country: United States

AGENCY: United States NIGMS

GRANT: R01 GM 54585

ACRONYM: GM

MEDLINETA: J Am Chem Soc

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