An olig2 reporter gene marks oligodendrocyte precursors in the postembryonic spinal cord of zebrafish.

An olig2 reporter gene marks oligodendrocyte precursors in the postembryonic spinal cord of zebrafish. Research Abstract Details 

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An olig2 reporter gene marks oligodendrocyte precursors in the postembryonic spinal cord of zebrafish. Abstract Text:

Hae-Chul Park,Jimann Shin,Randolph K Roberts,Bruce Appel,Hae-Chul Park,Jimann Shin,Randolph K Roberts,Bruce Appel,

Continuous production of new neurons and glia in adult mammals occurs within specialized proliferation zones of the forebrain. Neural cell proliferation and neurogenesis is more widespread in adult amphibians, reptiles, and fish but the identity of neural stem cell populations in these organisms has not been fully described. We investigated expression of a reporter gene driven by olig2 regulatory DNA at postembryonic stages in zebrafish. We show that olig2 expression marks a discrete population of spinal cord radial glia in larvae and adults that divide continuously. olig2(+) radial glia have hallmarks of stem cells and their divisions appear to be asymmetric, producing new oligodendrocytes but not neurons or astrocytes. Developmental Dynamics 236:3402-3407, 2007. (c) 2007 Wiley-Liss, Inc.

An olig2 reporter gene marks oligodendrocyte precursors in the postembryonic spinal cord of zebrafish. Publishing Authors By Initials

HC Park,J Shin,RK Roberts,B Appel,HC Park,J Shin,RK Roberts,B Appel,

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An olig2 reporter gene marks oligodendrocyte precursors in the postembryonic spinal cord of zebrafish. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Developmental dynamics : an official publication o

VOLUME: 236

Page Numbers: 3402-7

Journal Abbreviation: Dev. Dyn.

ISSN: 1058-8388

DAY: 26

MONTH: Dec

YEAR: 2007

An olig2 reporter gene marks oligodendrocyte precursors in the postembryonic spinal cord of zebrafish. Information

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LANGUAGE: eng

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Grant and Affiliation Information for An olig2 reporter gene marks oligodendrocyte precursors in the postembryonic spinal cord of zebrafish.

AFFILIATION: Graduate School of Medicine, Korea University, Ansan, Gyeonggido, Republic of Korea.

Country: United States

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