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An intragenic distribution bias of DNA uptake sequences in Pasteurellaceae and Neisseriae.

An intragenic distribution bias of DNA uptake sequences in Pasteurellaceae and Neisseriae. Research Abstract Details 

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  • An intragenic distribution bias of DNA uptake sequences in Pasteurellaceae and Neisseriae. Abstract Text:

    ABSTRACT: : Most sequenced strains from Pasteurellaceae and Neisseriae contain hundreds to thousands of uptake sequence (US) motifs in their genome, which are associated with natural competence for DNA uptake. The mechanism of their recognition is still unclear, and I searched for intragenic location patterns of these motifs for clues about their distribution. In all cases, one orientation of the US has a higher occurrence in the reading frame, and in all Pasteurellaceae, the US and the reverse complement motifs are biased towards the gene termini. These findings could help design experimental set-ups to study preferential DNA uptake, thereby further unravelling the phenomenon of natural competence. REVIEWERS: This article was reviewed by Arcady Mushegian and I. King Jordan.

    An intragenic distribution bias of DNA uptake sequences in Pasteurellaceae and Neisseriae. Publishing Authors By Initials

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    An intragenic distribution bias of DNA uptake sequences in Pasteurellaceae and Neisseriae. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Biology direct

    VOLUME: 3

    Page Numbers: 12

    Journal Abbreviation: Biol. Direct

    ISSN: 1745-6150

    DAY: 27

    MONTH: 03

    YEAR: 2008

    An intragenic distribution bias of DNA uptake sequences in Pasteurellaceae and Neisseriae. Information

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    LANGUAGE: eng

    NlmUniqueID: 101258412

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    Grant and Affiliation Information for An intragenic distribution bias of DNA uptake sequences in Pasteurellaceae and Neisseriae.

    AFFILIATION: Laboratory of Microbiology, Wageningen University, Dreijenplein 10, 6703 HB, Wageningen, The Netherlands. Mark.vanPassel@wur.nl.

    Country: England

    England Research PublicationEngland Research Publication

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    MEDLINETA: Biol Direct

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