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An immunohistochemical evaluation of BMP-2, -4, osteopontin, osteocalcin and PCNA between ossifying fibromas of the jaws and peripheral cemento-ossifying fibromas on the gingiva.

An immunohistochemical evaluation of BMP-2, -4, osteopontin, osteocalcin and PCNA between ossifying fibromas of the jaws and peripheral cemento-ossifying fibromas on the gingiva. Research Abstract Details 

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  • An immunohistochemical evaluation of BMP-2, -4, osteopontin, osteocalcin and PCNA between ossifying fibromas of the jaws and peripheral cemento-ossifying fibromas on the gingiva. Abstract Text:

    akiko onoAkiko Ono,goichi tsukamotoGoichi Tsukamoto,hitoshi nagatsukaHitoshi Nagatsuka,yasuto yoshihamaYasuto Yoshihama,rosario santos riveraRosario Santos Rivera,miki katsuranoMiki Katsurano,mayumi yaoMayumi Yao,akira sasakiAkira Sasaki,

    The present study examined histological difference between ossifying fibromas (OF, n=5) and peripheral cemento-ossifying fibromas (PCOF, n=7). Bone morphogenetic proteins (BMP)-2 and -4, osteopontin (OPN), osteocalcin (OCN) and proliferating cell nuclear antigen (PCNA) were used for the immunohistochemical examinations. Oxytalan fibers present at the periodontal tissue were stained to determine the tumor cell origin. Many OFs showed high immunohistochemical reactions for BMP-2, -4 and OPN compared to those of PCOFs. PCNA index (IP) of OFs was significantly higher than that of PCOFs. All the PCOFs showed a high expression of oxytalan fibers. Only two OFs exhibited a small number of oxytalan fibers. These results suggest that PCOF has only little ability to form hard tissue and seems to be a reactive lesion. The expression of oxytalan fibers reveals that OF does not only originate from periodontal tissue.

    An immunohistochemical evaluation of BMP-2, -4, osteopontin, osteocalcin and PCNA between ossifying fibromas of the jaws and peripheral cemento-ossifying fibromas on the gingiva. Publishing Authors By Initials

    a onoA Ono,g tsukamotoG Tsukamoto,h nagatsukaH Nagatsuka,y yoshihamaY Yoshihama,rs riveraRS Rivera,m katsuranoM Katsurano,m yaoM Yao,a sasakiA Sasaki,

    For similar peptides: intercellular signaling peptides and proteins: cytokines: transforming growth factor beta research abstracts see: peptides: intercellular signaling peptides and proteins: cytokines: transforming growth factor beta research

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    An immunohistochemical evaluation of BMP-2, -4, osteopontin, osteocalcin and PCNA between ossifying fibromas of the jaws and peripheral cemento-ossifying fibromas on the gingiva. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Oral oncology

    VOLUME: 43

    Page Numbers: 339-44

    Journal Abbreviation: Oral Oncol.

    ISSN: 1368-8375

    DAY: 22

    MONTH: 08

    YEAR: 2006

    An immunohistochemical evaluation of BMP-2, -4, osteopontin, osteocalcin and PCNA between ossifying fibromas of the jaws and peripheral cemento-ossifying fibromas on the gingiva. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 9709118

    An immunohistochemical evaluation of BMP-2, -4, osteopontin, osteocalcin and PCNA between ossifying fibromas of the jaws and peripheral cemento-ossifying fibromas on the gingiva. Keywords Mesh Terms:

    KEYWORDS: Transforming Growth Factor beta

    MESH TERMS: metabolism

    Chemical & Substance for Abstract: An immunohistochemical evaluation of BMP-2, -4, osteopontin, osteocalcin and PCNA between ossifying fibromas of the jaws and peripheral cemento-ossifying fibromas on the gingiva. Information

    Substance Name: Osteopontin

    Registry Number: 106441-73-0

    Grant and Affiliation Information for An immunohistochemical evaluation of BMP-2, -4, osteopontin, osteocalcin and PCNA between ossifying fibromas of the jaws and peripheral cemento-ossifying fibromas on the gingiva.

    AFFILIATION: Department of Oral and Maxillofacial Surgery, Biopathological Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama 700-8525, Japan.

    Country: England

    England Research PublicationEngland Research Publication

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    MEDLINETA: Oral Oncol

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    An immunohistochemical evaluation of BMP-2, -4, osteopontin, osteocalcin and PCNA between ossifying fibromas of the jaws and peripheral cemento-ossifying fibromas on the gingiva Related Publications

     

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