An association of NAG levels and a mutation of the CCK gene in panic disorder patients.

An association of NAG levels and a mutation of the CCK gene in panic disorder patients. Research Abstract Details 

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An association of NAG levels and a mutation of the CCK gene in panic disorder patients. Abstract Text:

Levels of the enzyme N-acetyl-beta-glucosaminidase (NAG) and a mutation of cholecystokinin (CCK) gene appear to be independently associated with panic disorder. We explored whether there was an association of NAG levels and a CCK mutation identified in a group of panic disorder patients. NAG was measured in 12 panic disorder patients who had a mutation of the CCK gene and 17 who did not. Urine for NAG was collected at baseline and after 3 and 6 weeks of treatment. NAG levels were lower at all three times in the patients that did not have the CCK mutation. The difference between the two groups was significant at week 6 (P < 0.02), and showed a trend toward a difference at baseline (P < 0.15).

An association of NAG levels and a mutation of the CCK gene in panic disorder patients. Publishing Authors By Initials

For similar mental disorders: anxiety disorders: panic disorder research abstracts see: mental disorders: anxiety disorders: panic disorder research

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An association of NAG levels and a mutation of the CCK gene in panic disorder patients. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Psychiatry research

VOLUME: 80

Page Numbers: 149-53

Journal Abbreviation: Psychiatry Res

ISSN: 0165-1781

DAY: 17

MONTH: Aug

YEAR: 1998

An association of NAG levels and a mutation of the CCK gene in panic disorder patients. Information

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LANGUAGE: eng

NlmUniqueID: 7911385

An association of NAG levels and a mutation of the CCK gene in panic disorder patients. Keywords Mesh Terms:

KEYWORDS: Panic Disorder

MESH TERMS: genetics

Chemical & Substance for Abstract: An association of NAG levels and a mutation of the CCK gene in panic disorder patients. Information

Substance Name: Acetylglucosaminidase

Registry Number: EC 3.2.1.52

Grant and Affiliation Information for An association of NAG levels and a mutation of the CCK gene in panic disorder patients.

AFFILIATION: Department of Psychiatry, VA Medical Center, University of Iowa College of Medicine, Iowa City 52246, USA.

Country: IRELAND

AGENCY: United States NIMH

GRANT: R01MH34728

ACRONYM: MH

MEDLINETA: Psychiatry Res

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