An analytical formula to estimate confidence interval of QTL location with a saturated genetic map as a function of experimental design.

An analytical formula to estimate confidence interval of QTL location with a saturated genetic map as a function of experimental design. Research Abstract Details 

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An analytical formula to estimate confidence interval of QTL location with a saturated genetic map as a function of experimental design. Abstract Text:

Joel Ira Weller,Morris Soller,

Analytical formulae are derived for the confidence interval for location of a quantitative trait locus (QTL) using a saturated genetic map, as a function of the experimental design, the QTL allele substitution effect, and the number of individuals genotyped and phenotyped. The formulae are derived assuming evenly spaced recombination events, rather than the actual unevenly spaced distribution. The formulae are useful for determining desired sample size when designing a wide variety of QTL mapping experiments, and for evaluating a priori the potential of a given mapping population for defining the location of a QTL. The formulae do not take into account the finite number of recombination events in a given sample.

An analytical formula to estimate confidence interval of QTL location with a saturated genetic map as a function of experimental design. Publishing Authors By Initials

JI Weller,M Soller,

For similar genetic processes: recombination, genetic research abstracts see: genetic processes: recombination, genetic research

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An analytical formula to estimate confidence interval of QTL location with a saturated genetic map as a function of experimental design. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: TAG. Theoretical and applied genetics. Theoretisch

VOLUME: 109

Page Numbers: 1224-9

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ISSN: 0040-5752

DAY: 23

MONTH: 09

YEAR: 2004

An analytical formula to estimate confidence interval of QTL location with a saturated genetic map as a function of experimental design. Information

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LANGUAGE: eng

NlmUniqueID: 145600

An analytical formula to estimate confidence interval of QTL location with a saturated genetic map as a function of experimental design. Keywords Mesh Terms:

KEYWORDS: Recombination, Genetic

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Grant and Affiliation Information for An analytical formula to estimate confidence interval of QTL location with a saturated genetic map as a function of experimental design.

AFFILIATION: Institute of Animal Sciences, Agricultural Research Organization, The Volcani Center, P.O. Box 6, Bet Dagan, 50250, Israel. weller@agri.huji.ac.il.

Country: Germany

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MEDLINETA: Theor Appl Genet

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