[An analysis of the relationship between HBV DNA and HBeAg expression and mortality in 799 severe hepatitis patients]

[An analysis of the relationship between HBV DNA and HBeAg expression and mortality in 799 severe hepatitis patients] Research Abstract Details 

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[An analysis of the relationship between HBV DNA and HBeAg expression and mortality in 799 severe hepatitis patients] Abstract Text:

Rong-bing Wang,Gui-qin Zhou,Yu-yong Jiang,Feng-xia Sun,Yun-zhong Wu,Jing-yuan Sun,Pei-pei Meng,Si-meng Niu,

OBJECTIVE: To evaluate the relationship between mortality and HBVDNA and HBeAg expression of severe hepatitis B patients. METHODS: The mortality rates of different types of severe hepatitis patients in our hospital during the last five years were anylysed. HBV DNA was detected using the fluorescence quantitative PCR method and the HBeAg expression of severe hepatitis B was studied using a microparticle method. RESULTS: (1) Hepatitis B morbidity was 83.5% in each type of severe hepatitis, and severe chronic hepatitis B morbidity was 96.77% in each type of severe chronic hepatitis. (2) The mortality rate of those with HBV DNA more than 1 x 10(5) copies/ml was 53.25% and the mortality of those with HBV DNA less than 1 x 10(5) copies/ml was 34.50% (P less than 0.01). The HBeAg expression had no influence on the death rate. (3) The death rate descended to 30.38% from 54.64% (HBV DNA more than 1 x 10(5) copies/ml) when treated with Lamivudine (P less than 0.01). CONCLUSION: In severe hepatitis the quantity of virus carried in the patient is one of the key factors of mortality; antivirus treatment can lower mortality.

[An analysis of the relationship between HBV DNA and HBeAg expression and mortality in 799 severe hepatitis patients] Publishing Authors By Initials

RB Wang,GQ Zhou,YY Jiang,FX Sun,YZ Wu,JY Sun,PP Meng,SM Niu,

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[An analysis of the relationship between HBV DNA and HBeAg expression and mortality in 799 severe hepatitis patients] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbi

VOLUME: 14

Page Numbers: 655-7

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ISSN: 1007-3418

DAY: 25

MONTH: Sep

YEAR: 2006

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LANGUAGE: chi

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Grant and Affiliation Information for [An analysis of the relationship between HBV DNA and HBeAg expression and mortality in 799 severe hepatitis patients]

AFFILIATION: Department of Infectious Diseases, Beijing Ditan Hospital, Beijing 100011, China.

Country: China

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MEDLINETA: Zhonghua Gan Zang Bing Za Zhi

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