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Amyloidosis in ageing obese-hyperglycemic mice and their lean litter-mates. A morphological study.

Amyloidosis in ageing obese-hyperglycemic mice and their lean litter-mates. A morphological study. Research Abstract Details 

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  • Amyloidosis in ageing obese-hyperglycemic mice and their lean litter-mates. A morphological study. Abstract Text:

    p naeserP Naeser,p westermarkP Westermark,

    The occurrence of amyloidosis in obese-hyperglycemic mice (genotype obob) about 18 months old and their lean litter-mates was studied. Amyloidosis of varying degrees was found in 60 per cent of the mice and was equally common in both groups. Large amounts of amyloid were usually seen in the adrenal glands, liver, spleen and kidneys. In the kidneys, the amyloid was found mainly in the glomeruli, in the mesangial region. Electron microscopy of isolated amyloid fibrils showed that these consisted of two filaments about 40 A thick, twisted around each other. It is concluded that the distribution of the amyloidosis in these mice is similar to that seen in secondary or experimental murine amyloidosis.

    Amyloidosis in ageing obese-hyperglycemic mice and their lean litter-mates. A morphological study. Publishing Authors By Initials

    p naeserP Naeser,p westermarkP Westermark,

    For similar tissues: lymphoid tissue: spleen research abstracts see: tissues: lymphoid tissue: spleen research

    PUBMED ID PMID:

    MEDLINE DATE:

    Amyloidosis in ageing obese-hyperglycemic mice and their lean litter-mates. A morphological study. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Acta pathologica et microbiologica Scandinavica. S

    VOLUME: 85

    Page Numbers: 761-7

    Journal Abbreviation:

    ISSN: 0365-4184

    DAY: 20

    MONTH: Nov

    YEAR: 1977

    Amyloidosis in ageing obese-hyperglycemic mice and their lean litter-mates. A morphological study. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 7508468

    Amyloidosis in ageing obese-hyperglycemic mice and their lean litter-mates. A morphological study. Keywords Mesh Terms:

    KEYWORDS: Spleen

    MESH TERMS: pathology

    Chemical & Substance for Abstract: Amyloidosis in ageing obese-hyperglycemic mice and their lean litter-mates. A morphological study. Information

    Substance Name: Amyloid

    Registry Number: 0

    Grant and Affiliation Information for Amyloidosis in ageing obese-hyperglycemic mice and their lean litter-mates. A morphological study.

    AFFILIATION:

    Country: DENMARK

    DENMARK Research PublicationDENMARK Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Acta Pathol Microbiol Scand [A

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

    Number Hits: 0

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