Altered MUC1 and MUC2 glycoprotein expression in laryngeal cancer.

Altered MUC1 and MUC2 glycoprotein expression in laryngeal cancer. Research Abstract Details 

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Altered MUC1 and MUC2 glycoprotein expression in laryngeal cancer. Abstract Text:

J P Jeannon,F W Stafford,J V Soames,J A Wilson,

The purpose of this study was to determine whether mucin expression is altered in laryngeal cancer. MUC1 and MUC2 mucin expression was examined in biopsy specimens from 80 patients that comprised 23 laryngeal dysplasias, 36 laryngeal carcinomas, and 21 normal larynx control specimens. High MUC1 expression was found in all 3 groups (P = 0.689, Fisher exact test). However, significantly higher levels of MUC2 expression were detected in carcinomas compared with dysplasias and control specimens (P = 0.009, Fisher exact test). Altered MUC2 expression may be an important step in carcinogenesis in laryngeal cancer.

Altered MUC1 and MUC2 glycoprotein expression in laryngeal cancer. Publishing Authors By Initials

JP Jeannon,FW Stafford,JV Soames,JA Wilson,

For similar biological factors: biological markers: tumor markers, biological research abstracts see: biological factors: biological markers: tumor markers, biological research

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Altered MUC1 and MUC2 glycoprotein expression in laryngeal cancer. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Otolaryngology--head and neck surgery : official j

VOLUME: 124

Page Numbers: 199-202

Journal Abbreviation:

ISSN: 0194-5998

DAY: 30

MONTH: Feb

YEAR: 2001

Altered MUC1 and MUC2 glycoprotein expression in laryngeal cancer. Information

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LANGUAGE: eng

NlmUniqueID: 8508176

Altered MUC1 and MUC2 glycoprotein expression in laryngeal cancer. Keywords Mesh Terms:

KEYWORDS: Tumor Markers, Biological

MESH TERMS: metabolism

Chemical & Substance for Abstract: Altered MUC1 and MUC2 glycoprotein expression in laryngeal cancer. Information

Substance Name: Tumor Markers, Biological

Registry Number: 0

Grant and Affiliation Information for Altered MUC1 and MUC2 glycoprotein expression in laryngeal cancer.

AFFILIATION: Department of Otolaryngology, Woodford Williams Building, Sunderland Royal Hospital, Kayll Road, Sunderland, SR4 7TP, Tyne & Wear, UK.

Country: United States

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MEDLINETA: Otolaryngol Head Neck Surg

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