Alpha-1-antitrypsin in malakoplakia.

Alpha-1-antitrypsin in malakoplakia. Research Abstract Details 

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Alpha-1-antitrypsin in malakoplakia. Abstract Text:

F Callea,B Van Damme,V J Desmet,

Macrophages in malakoplakia contain large amounts of immunoreactive alpha-1-antitrypsin (AAT). The amount of AAT remains unchanged during the morphogenetic stages of the pathological process (early, granulomatous, fibrosing phases), and does not correlate with the number or the presence of Michaelis-Gutmann (M.G.) bodies. Macrophages from other pathological processes, closely resembling malakoplakia cells but without M.G. bodies, did not contain AAT, except for a few macrophages in tuberculosis and xanthogranulomatous pyelonephritis. Whatever the source and the pathogenic role of AAT in malakoplakia, its presence in all macrophages seems to be specific for this disease. Immunohistochemical staining for AAT is therefore proposed as a useful test for an early and accurate differential diagnosis of malakoplakia.

Alpha-1-antitrypsin in malakoplakia. Publishing Authors By Initials

F Callea,B Van Damme,VJ Desmet,

For similar peptides: proteinase inhibitory proteins, secretory: alpha 1-antitrypsin research abstracts see: peptides: proteinase inhibitory proteins, secretory: alpha 1-antitrypsin research

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Alpha-1-antitrypsin in malakoplakia. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Virchows Archiv. A, Pathological anatomy and histo

VOLUME: 395

Page Numbers: 1-9

Journal Abbreviation:

ISSN: 0340-1227

DAY: 20

MONTH: 02

YEAR: 1982

Alpha-1-antitrypsin in malakoplakia. Information

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LANGUAGE: eng

NlmUniqueID: 7505137

Alpha-1-antitrypsin in malakoplakia. Keywords Mesh Terms:

KEYWORDS: alpha 1-Antitrypsin

MESH TERMS: analysis

Chemical & Substance for Abstract: Alpha-1-antitrypsin in malakoplakia. Information

Substance Name: alpha 1-Antitrypsin

Registry Number: 0

Grant and Affiliation Information for Alpha-1-antitrypsin in malakoplakia.

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Country: GERMANY, WEST

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MEDLINETA: Virchows Arch A Pathol Anat Hi

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