Alpha-1-antitrypsin globules in liver biopsies.

Alpha-1-antitrypsin globules in liver biopsies. Research Abstract Details 

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Alpha-1-antitrypsin globules in liver biopsies. Abstract Text:

P P Clausen,

In order to examine the frequency of alpha-1-antitrypsin (AAT) deficiency of phenotype Pi-Z in a consecutive liver biopsy material, PAS/diastase resistent globules with positive immunohistochemical reaction for AAT (AAT globules) were used as a marker of the Pi-Z gene. 34 (4%) of 850 liver biopsies contained AAT globules. More than half of the biopsies with globules had chief histological diagnoses within the groups fibrosis, suspicion of cirrhosis and cirrhosis. Micronodular cirrhosis was significantly more frequent in biopsies with AAT globules. The results support the assumption that AAT deficiency of phenotype Pi-Z as well in homozygous as heterozygous form is associated with development of liver cirrhosis.

Alpha-1-antitrypsin globules in liver biopsies. Publishing Authors By Initials

PP Clausen,

For similar skin and connective tissue diseases: connective tissue diseases: alpha 1-antitrypsin deficiency research abstracts see: skin and connective tissue diseases: connective tissue diseases: alpha 1-antitrypsin deficiency research

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Alpha-1-antitrypsin globules in liver biopsies. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Acta pathologica et microbiologica Scandinavica. S

VOLUME: 88

Page Numbers: 225-30

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ISSN: 0365-4184

DAY: 20

MONTH: Jul

YEAR: 1980

Alpha-1-antitrypsin globules in liver biopsies. Information

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LANGUAGE: eng

NlmUniqueID: 7508468

Alpha-1-antitrypsin globules in liver biopsies. Keywords Mesh Terms:

KEYWORDS: alpha 1-Antitrypsin Deficiency

MESH TERMS: analysis

Chemical & Substance for Abstract: Alpha-1-antitrypsin globules in liver biopsies. Information

Substance Name: alpha 1-Antitrypsin

Registry Number: 0

Grant and Affiliation Information for Alpha-1-antitrypsin globules in liver biopsies.

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Country: DENMARK

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MEDLINETA: Acta Pathol Microbiol Scand [A

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