Allosterically activated Diels-Alder catalysis by a ribozyme.

Allosterically activated Diels-Alder catalysis by a ribozyme. Research Abstract Details 

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Allosterically activated Diels-Alder catalysis by a ribozyme. Abstract Text:

Mark Helm,Markus Petermeier,Bixia Ge,Roberto Fiammengo,Andres ,

We describe the allosteric control of Diels-Alder reactions by a small organic effector, theophylline. This is achieved by converting a Diels-Alder ribozyme into an allosterically regulated system. In contrast to other published systems, we have a bond-forming reaction with two small-molecule substrates and multiple turnover. This system could be very attractive for the development of assays for a variety of analytes and can be regarded as a prototype of fully synthetic signaling cascades.

Allosterically activated Diels-Alder catalysis by a ribozyme. Publishing Authors By Initials

M Helm,M Petermeier,B Ge,R Fiammengo,A ,

For similar proteins: viral proteins research abstracts see: proteins: viral proteins research

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Allosterically activated Diels-Alder catalysis by a ribozyme. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of the American Chemical Society

VOLUME: 127

Page Numbers: 10492-3

Journal Abbreviation: J. Am. Chem. Soc.

ISSN: 0002-7863

DAY: 3

MONTH: Aug

YEAR: 2005

Allosterically activated Diels-Alder catalysis by a ribozyme. Information

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LANGUAGE: eng

NlmUniqueID: 7503056

Allosterically activated Diels-Alder catalysis by a ribozyme. Keywords Mesh Terms:

KEYWORDS: Viral Proteins

MESH TERMS: chemistry

Chemical & Substance for Abstract: Allosterically activated Diels-Alder catalysis by a ribozyme. Information

Substance Name: DNA-Directed RNA Polymerases

Registry Number: EC 2.7.7.6

Grant and Affiliation Information for Allosterically activated Diels-Alder catalysis by a ribozyme.

AFFILIATION: Institute of Pharmacy and Molecular Biotechnology, University of Heidelberg, Im Neuenheimer Feld 364, 69120 Heidelberg, Germany.

Country: United States

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MEDLINETA: J Am Chem Soc

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Allosterically activated Diels-Alder catalysis by a ribozyme Related Publications

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