Alkyl hydroperoxide reductase dependent on thioredoxin-like protein from Pyrococcus horikoshii.

Alkyl hydroperoxide reductase dependent on thioredoxin-like protein from Pyrococcus horikoshii. Research Abstract Details 

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Alkyl hydroperoxide reductase dependent on thioredoxin-like protein from Pyrococcus horikoshii. Abstract Text:

Yasuhiro Kashima,Kazuhiko Ishikawa,

Pyrococcus horikoshii is an obligate anaerobic hyperthermophilic archaeon. In P. horikoshii cells, a hydroperoxide reductase homologue ORF (PH1217) was found to be induced by oxygen. The recombinant protein, which was expressed in E. coli under aerobic conditions, exhibited no activity. However, the recombinant protein prepared under semi-anaerobic conditions exhibited alkyl hydroperoxide reductase activity. Furthermore, it was clarified that it was coupled with the thioredoxin-like system in P. horikoshii. Western blot analysis revealed that the protein was induced by oxygen and hydrogen peroxide. This protein seems to be sensitive to oxygen but forms a thioredoxin-dependent system to eliminate reactive oxygen species in P. horikoshii.

Alkyl hydroperoxide reductase dependent on thioredoxin-like protein from Pyrococcus horikoshii. Publishing Authors By Initials

Y Kashima,K Ishikawa,

For similar proteins: thioredoxins research abstracts see: proteins: thioredoxins research

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Alkyl hydroperoxide reductase dependent on thioredoxin-like protein from Pyrococcus horikoshii. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of biochemistry

VOLUME: 134

Page Numbers: 25-9

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Jul

YEAR: 2003

Alkyl hydroperoxide reductase dependent on thioredoxin-like protein from Pyrococcus horikoshii. Information

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LANGUAGE: eng

NlmUniqueID: 376600

Alkyl hydroperoxide reductase dependent on thioredoxin-like protein from Pyrococcus horikoshii. Keywords Mesh Terms:

KEYWORDS: Thioredoxins

MESH TERMS: metabolism

Chemical & Substance for Abstract: Alkyl hydroperoxide reductase dependent on thioredoxin-like protein from Pyrococcus horikoshii. Information

Substance Name: Thioredoxin-Disulfide Reductase

Registry Number: EC 1.8.1.9

Grant and Affiliation Information for Alkyl hydroperoxide reductase dependent on thioredoxin-like protein from Pyrococcus horikoshii.

AFFILIATION: Special Division of Human Life Technology, National Institute of Advanced Industrial Science and Technology (AIST Kansai) 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577.

Country: Japan

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MEDLINETA: J Biochem

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