Alfuzosin-induced hepatotoxicity.

Alfuzosin-induced hepatotoxicity. Research Abstract Details 

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Alfuzosin-induced hepatotoxicity. Abstract Text:

Drug-induced hepatic injury is a potential complication of virtually all drugs because the liver is central to the metabolic disposition of almost all drugs, although precise mechanisms often are unknown. We report a case of severe acute mixed hepatitis (cholestatic and hepatocellular), probably induced by alfuzosin. This event has not been reported previously (MEDLINE 1990, March 1999). Viral causes, autoimmune hepatitis and biliary tree obstruction were excluded. After discontinuation of the drug, liver function test results returned to normal.

Alfuzosin-induced hepatotoxicity. Publishing Authors By Initials

For similar heterocyclic compounds: heterocyclic compounds, 2-ring: quinazolines research abstracts see: heterocyclic compounds: heterocyclic compounds, 2-ring: quinazolines research

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Alfuzosin-induced hepatotoxicity. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of clinical pharmacy and therapeutics

VOLUME: 25

Page Numbers: 73-4

Journal Abbreviation: J Clin Pharm Ther

ISSN: 0269-4727

DAY: 28

MONTH: Feb

YEAR: 2000

Alfuzosin-induced hepatotoxicity. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8704308

Alfuzosin-induced hepatotoxicity. Keywords Mesh Terms:

KEYWORDS: Quinazolines

MESH TERMS: adverse effects

Chemical & Substance for Abstract: Alfuzosin-induced hepatotoxicity. Information

Substance Name: alfuzosin

Registry Number: 81403-80-7

Grant and Affiliation Information for Alfuzosin-induced hepatotoxicity.

AFFILIATION: Service of Internal Medicine, Hospital Obispo Polanco, Avda. Ruiz Jarabo s/n, E-44002 Teruel, Spain. 222438@cunit.unizar.es

Country: ENGLAND

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MEDLINETA: J Clin Pharm Ther

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