Alcohol and gastric acid secretion in humans: a short review.

Alcohol and gastric acid secretion in humans: a short review. Research Abstract Details 

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Alcohol and gastric acid secretion in humans: a short review. Abstract Text:

M V Singer,C Leffmann,

The action of ethanol and alcoholic beverages on gastric acid secretion and release of gastrin in healthy, nonalcoholic humans is reviewed. Intravenous ethanol causes a dose-dependent stimulation of gastric acid output without releasing gastrin. The action of intragastric instillation of pure ethanol on gastric acid secretion is related to its concentration: concentrations of 1.4% and 4% (v/v) are moderate stimulants; concentrations of 5% to 40% (w/v) have no or rather an inhibitory effect. Oral, intragastric, and intraduodenal administrations of ethanol do not release gastrin, whereas beer and white and red wine but not whisky and cognac are potent stimulants of gastric acid secretion and release gastrin in humans. The stimulatory mechanism of low ethanol concentrations is unknown. Nonalcoholic constituents of beer and wine are most likely responsible for the strong stimulatory action of both beverages on gastric acid secretion and release of gastrin.

Alcohol and gastric acid secretion in humans: a short review. Publishing Authors By Initials

MV Singer,C Leffmann,

For similar chemical and pharmacologic phenomena: stimulation, chemical research abstracts see: chemical and pharmacologic phenomena: stimulation, chemical research

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Alcohol and gastric acid secretion in humans: a short review. Journal Published:

PUBLICATION TYPE: Review

Journal: Scandinavian journal of gastroenterology. Suppleme

VOLUME: 146

Page Numbers: 11-21

Journal Abbreviation: Scand. J. Gastroenterol. Suppl

ISSN: 0085-5928

DAY: 13

MONTH: 02

YEAR: 1988

Alcohol and gastric acid secretion in humans: a short review. Information

Number of References: 47

LANGUAGE: eng

NlmUniqueID: 437034

Alcohol and gastric acid secretion in humans: a short review. Keywords Mesh Terms:

KEYWORDS: Stimulation, Chemical

MESH TERMS: secretion

Chemical & Substance for Abstract: Alcohol and gastric acid secretion in humans: a short review. Information

Substance Name: Ethanol

Registry Number: 64-17-5

Grant and Affiliation Information for Alcohol and gastric acid secretion in humans: a short review.

AFFILIATION: Dept. of Medicine, University of Essen, FRG.

Country: NORWAY

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MEDLINETA: Scand J Gastroenterol Suppl

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