Alcohol abusers exhibit a higher IgA response to acetaldehyde-modified proteins.

Alcohol abusers exhibit a higher IgA response to acetaldehyde-modified proteins. Research Abstract Details 

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Alcohol abusers exhibit a higher IgA response to acetaldehyde-modified proteins. Abstract Text:

In the present study we have used an enzyme-linked immunosorbent assay to measure the immunoreactivity towards acetaldehyde-modified proteins in plasma from alcoholics, patients with non-alcoholic liver disease and control social drinkers. All three groups showed a response to modified proteins when total immunoglobulin binding was measured. However, when the assay was modified such that class-specific immunoglobulin binding was measured, it was found that the alcoholic response had a significantly greater immunoglobulin A component than patients with non-alcoholic liver disease or controls who were social drinkers. Thus measurement of IgA binding to acetaldehyde-modified proteins may be a marker for alcohol abuse.

Alcohol abusers exhibit a higher IgA response to acetaldehyde-modified proteins. Publishing Authors By Initials

For similar digestive system diseases: liver diseases research abstracts see: digestive system diseases: liver diseases research

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Alcohol abusers exhibit a higher IgA response to acetaldehyde-modified proteins. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Alcohol and alcoholism (Oxford, Oxfordshire). Supp

VOLUME: 1

Page Numbers: 261-4

Journal Abbreviation:

ISSN: 1358-6173

DAY: 26

MONTH: 02

YEAR: 1991

Alcohol abusers exhibit a higher IgA response to acetaldehyde-modified proteins. Information

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LANGUAGE: eng

NlmUniqueID: 8804836

Alcohol abusers exhibit a higher IgA response to acetaldehyde-modified proteins. Keywords Mesh Terms:

KEYWORDS: Liver Diseases

MESH TERMS: immunology

Chemical & Substance for Abstract: Alcohol abusers exhibit a higher IgA response to acetaldehyde-modified proteins. Information

Substance Name: Acetaldehyde

Registry Number: 75-07-0

Grant and Affiliation Information for Alcohol abusers exhibit a higher IgA response to acetaldehyde-modified proteins.

AFFILIATION: Department of Biochemistry, University of Queensland, Australia.

Country: ENGLAND

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MEDLINETA: Alcohol Alcohol Suppl

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