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Aggressive metastasising adenocarcinoma of the retinal pigment epithelium with trisomy 21.

Aggressive metastasising adenocarcinoma of the retinal pigment epithelium with trisomy 21. Research Abstract Details 

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  • Aggressive metastasising adenocarcinoma of the retinal pigment epithelium with trisomy 21. Abstract Text:

    This case report describes a 37-year-old man with a blind eye with opaque media. Histopathology revealed an aggressive adenocarcinoma of the retinal pigment epithelium with marked invasion of the choroid, retina, sclera and--not previously reported--the orbital and cranial optic nerve and subarachnoid space. The tumour seeded into the lumbar spinal-cord space. Metastatic foci--not in continuity with the primary process--developed in the parietal lobe and cerebellopontine angle. Adenocarcinoma of the retinal pigment epithelium, which occurs rarely in longstanding blind eyes, may exhibit aggressive behaviour with life-threatening risk of metastatic spread.

    Aggressive metastasising adenocarcinoma of the retinal pigment epithelium with trisomy 21. Publishing Authors By Initials

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    Aggressive metastasising adenocarcinoma of the retinal pigment epithelium with trisomy 21. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: The British journal of ophthalmology

    VOLUME: 92

    Page Numbers: 389-91

    Journal Abbreviation:

    ISSN: 1468-2079

    DAY: 27

    MONTH: Mar

    YEAR: 2008

    Aggressive metastasising adenocarcinoma of the retinal pigment epithelium with trisomy 21. Information

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    LANGUAGE: eng

    NlmUniqueID: 421041

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    Grant and Affiliation Information for Aggressive metastasising adenocarcinoma of the retinal pigment epithelium with trisomy 21.

    AFFILIATION: Department of Ophthalmology and Eye Hospital, University Erlangen-Nürnberg, Schwabachanlage 6, 91054 Erlangen, Germany. ludwig.heindl@augen.imed.uni-erlangen.de

    Country: England

    England Research PublicationEngland Research Publication

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    MEDLINETA: Br J Ophthalmol

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