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Aggregation of fibronectin by asbestos fibers in the pericellular matrix of cultured human fibroblasts.

Aggregation of fibronectin by asbestos fibers in the pericellular matrix of cultured human fibroblasts. Research Abstract Details 

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  • Aggregation of fibronectin by asbestos fibers in the pericellular matrix of cultured human fibroblasts. Abstract Text:

    Asbestos fibers, silica dust and glass fibers induced aggregation of the pericellular matrix fibronectin when added to the growth medium of cultured human fibroblasts as judged by immunofluorescence microscopy. Direct binding experiments and analysis of the bound proteins by (SDS-polyacrylamide gel electrophoresis) revealed an adsorption of purified plasma fibronectin to glass fibers, amosite, crocidolite and silica but not to anthophyllite and chrysotile A and B. The results suggest that aggregation of the pericellular fibronectin by these fibrogenic materials may be involved in the initial stages of the development of fibrosis in vivo.

    Aggregation of fibronectin by asbestos fibers in the pericellular matrix of cultured human fibroblasts. Publishing Authors By Initials

    For similar biochemical phenomena, metabolism, and nutrition: biochemical phenomena: protein binding research abstracts see: biochemical phenomena, metabolism, and nutrition: biochemical phenomena: protein binding research

    PUBMED ID PMID:

    MEDLINE DATE:

    Aggregation of fibronectin by asbestos fibers in the pericellular matrix of cultured human fibroblasts. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Acta pathologica, microbiologica, et immunologica

    VOLUME: 94

    Page Numbers: 169-75

    Journal Abbreviation:

    ISSN: 0108-0164

    DAY: 26

    MONTH: May

    YEAR: 1986

    Aggregation of fibronectin by asbestos fibers in the pericellular matrix of cultured human fibroblasts. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 8206622

    Aggregation of fibronectin by asbestos fibers in the pericellular matrix of cultured human fibroblasts. Keywords Mesh Terms:

    KEYWORDS: Protein Binding

    MESH TERMS: ultrastructure

    Chemical & Substance for Abstract: Aggregation of fibronectin by asbestos fibers in the pericellular matrix of cultured human fibroblasts. Information

    Substance Name: Asbestos

    Registry Number: 1332-21-4

    Grant and Affiliation Information for Aggregation of fibronectin by asbestos fibers in the pericellular matrix of cultured human fibroblasts.

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    Country: DENMARK

    DENMARK Research PublicationDENMARK Research Publication

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    ACRONYM:

    MEDLINETA: Acta Pathol Microbiol Immunol

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