[Advances in therapeutic strategies for multiple myeloma.]

[Advances in therapeutic strategies for multiple myeloma.] Research Abstract Details 

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[Advances in therapeutic strategies for multiple myeloma.] Abstract Text:

Akiyoshi Miwa,Akiyoshi Miwa,Akiyoshi Miwa,

Multiple myeloma (MM) remains an incurable plasma cell dyscrasia characterized by bone marrow failure, bone disease, renal disease and other complications. The clinical picutures show extensive diversity which is based on complex cytogenetic abnormalities, and lot of interactions between myeloma cell and bone marrow stroma. Recently, advances in understanding the biology of myeloma including the function of proteasome, molecular chaperons on the folding of intracellular proteins as well as signal transduction pathway, apoptosis-inducing cascade and oncogenomics, have brought about the development of several new therapeutic strategies. This review summarizes the major innovative agents in this field and discuss the future directions.

[Advances in therapeutic strategies for multiple myeloma.] Publishing Authors By Initials

A Miwa,A Miwa,A Miwa,

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[Advances in therapeutic strategies for multiple myeloma.] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Gan to kagaku ryoho. Cancer & chemotherapy

VOLUME: 34

Page Numbers: 2200-16

Journal Abbreviation: Gan To Kagaku Ryoho

ISSN: 0385-0684

DAY: 14

MONTH: Dec

YEAR: 2007

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LANGUAGE: jpn

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AFFILIATION: Dept. of Hematology, International Medical Center of Japan.

Country: Japan

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MEDLINETA: Gan To Kagaku Ryoho

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