Advances in potential M-protein peptide-based vaccines for preventing rheumatic fever and rheumatic heart disease.

Advances in potential M-protein peptide-based vaccines for preventing rheumatic fever and rheumatic heart disease. Research Abstract Details 

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Advances in potential M-protein peptide-based vaccines for preventing rheumatic fever and rheumatic heart disease. Abstract Text:

Michael R Batzloff,Manisha Pandey,Colleen Olive,Michael F Good,

Rheumatic fever (RF) and rheumatic heart disease (RHD) are postinfectious complications of an infection (or repeated infection) with the Gram-positive bacterium, Streptococcus pyogenes (also known as group A streptococcus, GAS). RF and RHD are global problems and affect many indigenous populations of developed countries and many developing countries. However, RF and RHD are only part of a larger spectrum of diseases caused by this organism. The development of a vaccine against GAS has primarily targeted the abundant cell-surface protein called the M-protein. This review focuses on different M-protein-based-subunit vaccine approaches and the different delivery technologies used to administer these vaccine candidates in preclinical studies.

Advances in potential M-protein peptide-based vaccines for preventing rheumatic fever and rheumatic heart disease. Publishing Authors By Initials

MR Batzloff,M Pandey,C Olive,MF Good,

For similar complex mixtures: biological products: vaccines: vaccines, subunit research abstracts see: complex mixtures: biological products: vaccines: vaccines, subunit research

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Advances in potential M-protein peptide-based vaccines for preventing rheumatic fever and rheumatic heart disease. Journal Published:

PUBLICATION TYPE: Review

Journal: Immunologic research

VOLUME: 35

Page Numbers: 233-48

Journal Abbreviation: Immunol. Res.

ISSN: 0257-277X

DAY: 3

MONTH: 12

YEAR: 2006

Advances in potential M-protein peptide-based vaccines for preventing rheumatic fever and rheumatic heart disease. Information

Number of References: 77

LANGUAGE: eng

NlmUniqueID: 8611087

Advances in potential M-protein peptide-based vaccines for preventing rheumatic fever and rheumatic heart disease. Keywords Mesh Terms:

KEYWORDS: Vaccines, Subunit

MESH TERMS: immunology

Chemical & Substance for Abstract: Advances in potential M-protein peptide-based vaccines for preventing rheumatic fever and rheumatic heart disease. Information

Substance Name: Vaccines, Subunit

Registry Number: 0

Grant and Affiliation Information for Advances in potential M-protein peptide-based vaccines for preventing rheumatic fever and rheumatic heart disease.

AFFILIATION: The Cooperative Research Centre for Vaccine Technology and the Australian Centre for International Tropical Health and Nutrition, The Queensland Institute of Medical Research, Post Office Royal Brisbane Hospital, Brisbane 4029, Australia.

Country: United States

AGENCY: United States NIAID

GRANT: U01-AI060579-01

ACRONYM: AI

MEDLINETA: Immunol Res

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