Advances in pediatric asthma 2006.

Advances in pediatric asthma 2006. Research Abstract Details 

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Advances in pediatric asthma 2006. Abstract Text:

Stanley J Szefler,

Because the outcomes experienced in adult asthma often result from pathophysiology that begins in early childhood, this year's summary focuses on recent advances in pediatric asthma. This past year, we have learned that early intervention with inhaled corticosteroids in childhood asthma reduces morbidity but does not alter the natural history of asthma. Theme issues over the last year focused attention on severe asthma and black box warnings. Both of these themes significantly affect the management of childhood asthma. Responsiveness to asthma treatment is heterogeneous even among patients with asthma of similar severity. This heterogeneity calls attention to the importance of assessing control and adjusting treatment accordingly. We are now moving toward an individualized approach to asthma therapy and searching for biomarkers and genetics as a resource to guide treatment. To improve asthma control, we must continue to obtain information on early asthma, severe asthma, asthma exacerbations, and methods to improve asthma control. Evaluation and management of severe asthma in children include verification of the diagnosis, assessment for coexisting illnesses, and identification of effective treatment strategies directed to adherence, medication delivery, and combination therapy. Application of biomarkers and genetics could be useful tools in individualizing our approach to the management of childhood asthma.

Advances in pediatric asthma 2006. Publishing Authors By Initials

SJ Szefler,

For similar animals: chordata: vertebrates: mammals: primates: haplorhini: catarrhini: hominidae: humans research abstracts see: animals: chordata: vertebrates: mammals: primates: haplorhini: catarrhini: hominidae: humans research

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Advances in pediatric asthma 2006. Journal Published:

PUBLICATION TYPE: Review

Journal: The Journal of allergy and clinical immunology

VOLUME: 119

Page Numbers: 558-62

Journal Abbreviation: J. Allergy Clin. Immunol.

ISSN: 0091-6749

DAY: 30

MONTH: 01

YEAR: 2007

Advances in pediatric asthma 2006. Information

Number of References: 39

LANGUAGE: eng

NlmUniqueID: 1275002

Advances in pediatric asthma 2006. Keywords Mesh Terms:

KEYWORDS: Humans

MESH TERMS: analysis

Chemical & Substance for Abstract: Advances in pediatric asthma 2006. Information

Substance Name: Biological Markers

Registry Number: 0

Grant and Affiliation Information for Advances in pediatric asthma 2006.

AFFILIATION: Divisions of Pediatric Clinical Pharmacology, Allergy and Immunology, Department of Pediatrics, National Jewish Medical and Research Center, Denver, CO 80206, USA. szeflers@njc.org

Country: United States

AGENCY: United States NCRR

GRANT: M01 RR00051

ACRONYM: RR

MEDLINETA: J Allergy Clin Immunol

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