Adult T-cell leukemia/lymphoma in Bahia, Brazil: analysis of prognostic factors in a group of 70 patients.

Adult T-cell leukemia/lymphoma in Bahia, Brazil: analysis of prognostic factors in a group of 70 patients. Research Abstract Details 

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Adult T-cell leukemia/lymphoma in Bahia, Brazil: analysis of prognostic factors in a group of 70 patients. Abstract Text:

Bittencourt,Maria ,Carlos R Brites,Lourdes Farre,Helenemarie S Barbosa,

The purpose of this study was to evaluate whether subdivision of adult T-cell leukemia/lymphoma (ATL) on the basis of clinical types, skin involvement, histologic features, cell size, and proliferative index (PI) was clinically relevant. Skin lesions were present in 47 cases (67%). Five cases were classified as primary cutaneous tumoral (PCT) type not included in the Shimoyama classification and characterized by skin tumors and absence of systemic involvement, lymphocytosis, and hypercalcemia. Mortality was high (61/70 [87%]). The overall median survival time (MST) was 12 months. The following variables were adversely related to survival: acute, lymphoma, and PCT types; absence of skin lesions; large cells; and PI more than 18%. The longer MST observed in cases with skin lesions was probably due to prolonged survival of the smoldering type (58 months). The MST of the PCT type (21 months) was shorter than that of the smoldering type, confirming the importance of clearly defining these 2 types of ATL.

Adult T-cell leukemia/lymphoma in Bahia, Brazil: analysis of prognostic factors in a group of 70 patients. Publishing Authors By Initials

AL Bittencourt,M ,CR Brites,L Farre,HS Barbosa,

For similar investigative techniques: epidemiologic methods: data collection: vital statistics: mortality: survival rate research abstracts see: investigative techniques: epidemiologic methods: data collection: vital statistics: mortality: survival rate research

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Adult T-cell leukemia/lymphoma in Bahia, Brazil: analysis of prognostic factors in a group of 70 patients. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: American journal of clinical pathology

VOLUME: 128

Page Numbers: 875-82

Journal Abbreviation: Am. J. Clin. Pathol.

ISSN: 0002-9173

DAY: 29

MONTH: Nov

YEAR: 2007

Adult T-cell leukemia/lymphoma in Bahia, Brazil: analysis of prognostic factors in a group of 70 patients. Information

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LANGUAGE: eng

NlmUniqueID: 370470

Adult T-cell leukemia/lymphoma in Bahia, Brazil: analysis of prognostic factors in a group of 70 patients. Keywords Mesh Terms:

KEYWORDS: Survival Rate

MESH TERMS: pathology

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Grant and Affiliation Information for Adult T-cell leukemia/lymphoma in Bahia, Brazil: analysis of prognostic factors in a group of 70 patients.

AFFILIATION: Department of Pathology, Hospital Universitário Prof Edgard Santos, Federal University of Bahia, Brazil.

Country: United States

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MEDLINETA: Am J Clin Pathol

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