Adult respiratory distress syndrome after treatment with pegylated interferon alpha-2a and ribavirin.

Adult respiratory distress syndrome after treatment with pegylated interferon alpha-2a and ribavirin. Research Abstract Details 

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Adult respiratory distress syndrome after treatment with pegylated interferon alpha-2a and ribavirin. Abstract Text:

Edmond Vartany,Cary A Caldwell,Terence K Trow,

Pulmonary manifestations of interferon (IFN) use are a rare but well known complication seen with both standard and pegylated interferon alpha-2b (pegIFNalpha-2b) forms of the agent. These are generally of modest intensity and reversible. We report the first case of fulminant adult respiratory distress syndrome (ARDS) associated with pegylated interferon alpha-2a (pegIFNalpha-2a) and ribavirin use for hepatitis C, complicated by subsequent and ultimately fatal sepsis and multiorgan failure. Practicing gastroenterologists and intensivists alike need to be aware of the potential for serious pulmonary sequelae with the use of combination therapy for chronic hepatitis C viral (CHCV) infections.

Adult respiratory distress syndrome after treatment with pegylated interferon alpha-2a and ribavirin. Publishing Authors By Initials

E Vartany,CA Caldwell,TK Trow,

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Adult respiratory distress syndrome after treatment with pegylated interferon alpha-2a and ribavirin. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Heart & lung : the journal of critical care

VOLUME: 37

Page Numbers: 153-6

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ISSN: 1527-3288

DAY: 28

MONTH: 03

YEAR: 2008

Adult respiratory distress syndrome after treatment with pegylated interferon alpha-2a and ribavirin. Information

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LANGUAGE: eng

NlmUniqueID: 330057

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Grant and Affiliation Information for Adult respiratory distress syndrome after treatment with pegylated interferon alpha-2a and ribavirin.

AFFILIATION: Pulmonary and Critical Care Medicine, Norwalk Hospital, Norwalk, CT 06520-8057, USA.

Country: United States

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MEDLINETA: Heart Lung

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