Adolescent idiopathic scoliosis: natural history and long term treatment effects.

Adolescent idiopathic scoliosis: natural history and long term treatment effects. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Adolescent idiopathic scoliosis: natural history and long term treatment effects. Abstract Text:

Marc A Asher,Douglas C Burton,

ABSTRACT : Adolescent idiopathic scoliosis is a lifetime, probably systemic condition of unknown cause, resulting in a spinal curve or curves of ten degrees or more in about 2.5% of most populations. However, in only about 0.25% does the curve progress to the point that treatment is warranted.Untreated, adolescent idiopathic scoliosis does not increase mortality rate, even though on rare occasions it can progress to the >100 degrees range and cause premature death. The rate of shortness of breath is not increased, although patients with 50 degrees curves at maturity or 80 degrees curves during adulthood are at increased risk of developing shortness of breath. Compared to non-scoliotic controls, most patients with untreated adolescent idiopathic scoliosis function at or near normal levels. They do have increased pain prevalence and may or may not have increased pain severity. Self-image is often decreased. Mental health is usually not affected. Social function, including marriage and childbearing may be affected, but only at the threshold of relatively larger curves.Non-operative treatment consists of bracing for curves of 25 degrees to 35 degrees or 40 degrees in patients with one to two years or more of growth remaining. Curve progression of >/= 6 degrees is 20 to 40% more likely with observation than with bracing. Operative treatment consists of instrumentation and arthrodesis to realign and stabilize the most affected portion of the spine. Lasting curve improvement of approximately 40% is usually achieved.In the most completely studied series to date, at 20 to 28 years follow-up both braced and operated patients had similar, significant, and clinically meaningful reduced function and increased pain compared to non-scoliotic controls. However, their function and pain scores were much closer to normal than patient groups with other, more serious conditions.Risks associated with treatment include temporary decrease in self-image in braced patients. Operated patients face the usual risks of major surgery, a 6 to 29% chance of requiring re-operation, and the remote possibility of developing a pain management problem.Knowledge of adolescent idiopathic scoliosis natural history and long-term treatment effects is and will always remain somewhat incomplete. However, enough is know to provide patients and parents the information needed to make informed decisions about management options.

Adolescent idiopathic scoliosis: natural history and long term treatment effects. Publishing Authors By Initials

MA Asher,DC Burton,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Adolescent idiopathic scoliosis: natural history and long term treatment effects. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Scoliosis

VOLUME: 1

Page Numbers: 2

Journal Abbreviation:

ISSN: 1748-7161

DAY: 31

MONTH: 03

YEAR: 2006

Adolescent idiopathic scoliosis: natural history and long term treatment effects. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101271527

Adolescent idiopathic scoliosis: natural history and long term treatment effects. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Adolescent idiopathic scoliosis: natural history and long term treatment effects. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Adolescent idiopathic scoliosis: natural history and long term treatment effects.

AFFILIATION: Department of Orthopedic Surgery, University of Kansas Medical Center, Kansas City, KS, USA. masher@kumc.edu.

Country: England

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Scoliosis

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Adolescent idiopathic scoliosis: natural history and long term treatment effects Related Publications

• A novel thermostable nitrilase superfamily amidase from Geobacillus pallidus showing acyl transfer activity.
• Adolescent idiopathic scoliosis: natural history and long term treatment effects.
• Aminopterin might be safe in ALL.
• Analysis of the neutralization breadth of the anti-V3 antibody F425-B4e8 and re-assessment of its epitope fine specificity by scanning mutagenesis.
• Antibodies to West Nile virus: a double-edged sword.
• Antigenic and immunogenic study of membrane-proximal external region-grafted gp120 antigens by a DNA prime-protein boost immunization strategy.
• Biokinetics in humans of RRR-alpha-tocopherol: the free phenol, acetate ester, and succinate ester forms of vitamin E.
• Booklet-based education in vestibular rehabilitation or symptom control improved subjective health in Ménière disease.
• Diabetes expert accuses drug company of "intimidation".
• Dissecting the neutralizing antibody specificities of broadly neutralizing sera from human immunodeficiency virus type 1-infected donors.
• Does poor housing raise diabetes risk?
• Early African Diaspora in colonial Campeche, Mexico: strontium isotopic evidence.
• Effect of vitamin E on human glutathione peroxidase (GSH-PX1) expression in cardiomyocytes.
• Effects of masking noise on vowel and sibilant contrasts in normal-hearing speakers and postlingually deafened cochlear implant users.
• Generation of a transgenic zebrafish model of Tauopathy using a novel promoter element derived from the zebrafish eno2 gene.
• HIV-1 neutralization: mechanisms and relevance to vaccine design.
• Hits and false positives in face matching: a familiarity-based dissociation.
• Isonychia spp. and macroinvertebrate community responses to stressors in streams utilizing the benthic in situ toxicity identification evaluation (BiTIE) method.
• Metabolic cardiomyopathy and mitochondrial disorders in the pediatric intensive care unit.
• Morphological and biological effects of maternal exposure to tobacco smoke on the feto-placental unit.
• Neutralizing antibody fails to impact the course of Ebola virus infection in monkeys.
• Primary intracranial leiomyosarcoma: report of a case and review of the literature.
• Smokers' interest in using nicotine replacement to aid smoking reduction.
• Symptom domains of schizophrenia: the role of atypical antipsychotic agents.
• The Benefits of using MRI-CT Fused Images for Post-implant Prostate Dosimetry.
• Time course of speech changes in response to unanticipated short-term changes in hearing state.
• Use and approximation of the air mixing factor used in dilution ventilation in industrial settings.
• Validity of polygraphs.
• What's new in azithromyin?
• Withanolides from Jaborosa laciniata.