Adaptations in metabolic acidosis: a reinterpretation.

Adaptations in metabolic acidosis: a reinterpretation. Research Abstract Details 

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Adaptations in metabolic acidosis: a reinterpretation. Abstract Text:

J Oliver,E Bourke,

Hydrochloric-acid induced acidosis reduced urea excretion in the rat, with an equimolar increase in NH+4 excreation and no change in their sum. By contrast, in the guinea pig, where ammonium excretion is small, HC1 administration did not effect urea excretion. Ammonium administered as NH4HCO3 was excreted mainly in the form of urinary urea, whereas that administered as NH4C1 was mainly in the form of ammonium. Methionine sulphoximine did not impair the increased ammonium excretion induced by acidosis, but did lead to a marked decrease in plasma glutamine levels and an overall increase in total urinary urea and ammonium nitrogen excretion. A reinterpretation of some aspects of the adaptations to metabolic acidosis is made based on these findings.

Adaptations in metabolic acidosis: a reinterpretation. Publishing Authors By Initials

J Oliver,E Bourke,

For similar organic chemicals: urea research abstracts see: organic chemicals: urea research

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Adaptations in metabolic acidosis: a reinterpretation. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Proceedings of the European Dialysis and Transplan

VOLUME: 11

Page Numbers: 411-6

Journal Abbreviation:

ISSN: 0071-2736

DAY: 21

MONTH: 02

YEAR: 1975

Adaptations in metabolic acidosis: a reinterpretation. Information

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LANGUAGE: eng

NlmUniqueID: 355210

Adaptations in metabolic acidosis: a reinterpretation. Keywords Mesh Terms:

KEYWORDS: Urea

MESH TERMS: metabolism

Chemical & Substance for Abstract: Adaptations in metabolic acidosis: a reinterpretation. Information

Substance Name: Hydrochloric Acid

Registry Number: 7647-01-0

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Country: ENGLAND

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MEDLINETA: Proc Eur Dial Transplant Assoc

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