Adaptation of the pancreas during treatment with enzyme inhibitors in rats and man.

Adaptation of the pancreas during treatment with enzyme inhibitors in rats and man. Research Abstract Details 

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Adaptation of the pancreas during treatment with enzyme inhibitors in rats and man. Abstract Text:

U R Fölsch,W Creutzfeldt,

This report deals with the effect of feeding inhibitors of pancreatic and brush border enzymes on pancreatic growth and enzyme composition and secretion. Raw soybean flour containing trypsin inhibitors caused pronounced growth of the pancreas which was accompanied by increased enzyme content and increased CCK and gastrin concentration in the plasma. Feeding of an amylase inhibitor to a starch-rich diet induced a marked fall in amylase content and secretion without changing growth parameters of the pancreas, indicating that not starch but glucose is the trigger for the maintenance of amylase content and secretion of the pancreas. The addition of an alpha-glucosidase inhibitor (acarbose) to a sucrose- or maltose-rich semisynthetic diet did not cause significant alteration in pancreatic growth or enzyme composition or secretion. In man pancreatic function was also unaltered by 8 weeks' intake of 3 X 200 mg acarbose.

Adaptation of the pancreas during treatment with enzyme inhibitors in rats and man. Publishing Authors By Initials

UR Fölsch,W Creutzfeldt,

For similar enzymes and coenzymes: enzymes: hydrolases: glycoside hydrolases: glucosidases: alpha-glucosidases research abstracts see: enzymes and coenzymes: enzymes: hydrolases: glycoside hydrolases: glucosidases: alpha-glucosidases research

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Adaptation of the pancreas during treatment with enzyme inhibitors in rats and man. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Scandinavian journal of gastroenterology. Suppleme

VOLUME: 112

Page Numbers: 54-63

Journal Abbreviation: Scand. J. Gastroenterol. Suppl

ISSN: 0085-5928

DAY: 13

MONTH: 02

YEAR: 1985

Adaptation of the pancreas during treatment with enzyme inhibitors in rats and man. Information

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LANGUAGE: eng

NlmUniqueID: 437034

Adaptation of the pancreas during treatment with enzyme inhibitors in rats and man. Keywords Mesh Terms:

KEYWORDS: alpha-Glucosidases

MESH TERMS: antagonists & inhibitors

Chemical & Substance for Abstract: Adaptation of the pancreas during treatment with enzyme inhibitors in rats and man. Information

Substance Name: alpha-Glucosidases

Registry Number: EC 3.2.1.20

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Country: NORWAY

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MEDLINETA: Scand J Gastroenterol Suppl

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