Acute measles infection in the hamster cochlea.

Acute measles infection in the hamster cochlea. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Acute measles infection in the hamster cochlea. Abstract Text:

S Fukuda,K Ishikawa,Y Inuyama,

Measles virus has been implicated in sudden sensorineural hearing loss (SNHL) in adults as well as in children. Furthermore, sensorineural hearing loss following live measles virus vaccination has been reported. As of yet, however, there has been only few reports on human temporal bone pathology due to measles, and on experimental animal models of measles infection. This study was undertaken to examine acute measles infection in adult hamster cochlea morphologically and immunohistochemically for precise understanding of this viral infection. Atrophy of the stria vascularis, loss of the organ of Corti, "rolled-up" tectorial membrane, and cell infiltration with a positive immunofluorescent reaction primarily within the scale media indicating endolymphatic labyrinthitis were the principal findings. These results were generally consistent with previous ones on human temporal bone pathology not only due to measles but also to SNHL. We consider measles virus to be one of the possible pathogens, even if low in frequency, causing profound and irreversible hearing loss, including SNHL. Completion of measles vaccination without complication and selective or mass revaccination may be necessary to prevent such hearing loss.

Acute measles infection in the hamster cochlea. Publishing Authors By Initials

S Fukuda,K Ishikawa,Y Inuyama,

For similar ear, inner: cochlea: cochlear duct: tectorial membrane research abstracts see: ear, inner: cochlea: cochlear duct: tectorial membrane research

PUBMED ID PMID:

MEDLINE DATE:

Acute measles infection in the hamster cochlea. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Acta oto-laryngologica. Supplementum

VOLUME: 514

Page Numbers: 111-6

Journal Abbreviation:

ISSN: 0365-5237

DAY: 13

MONTH: 02

YEAR: 1994

Acute measles infection in the hamster cochlea. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 370355

Acute measles infection in the hamster cochlea. Keywords Mesh Terms:

KEYWORDS: Tectorial Membrane

MESH TERMS: pathology

Chemical & Substance for Abstract: Acute measles infection in the hamster cochlea. Information

Substance Name: Antigens, Viral

Registry Number: 0

Grant and Affiliation Information for Acute measles infection in the hamster cochlea.

AFFILIATION: Department of Otolaryngology, Hokkaido University School of Medicine, Sapporo, Japan.

Country: NORWAY

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Acta Otolaryngol Suppl

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Acute measles infection in the hamster cochlea Related Publications

• Acute measles infection in the hamster cochlea.
• Spiral modiolar vein: its importance in viral load of the inner ear.