Acute IGF-1 deficiency in multiple trauma victims.

Acute IGF-1 deficiency in multiple trauma victims. Research Abstract Details 

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Acute IGF-1 deficiency in multiple trauma victims. Abstract Text:

M Jeevanandam,N J Holaday,R F Shamos,S R Petersen,

The circulating levels of IGF-1 in the catabolic flow phase of injury were measured in multiple trauma victims once before nutritional support and again after 4 days of intravenous feeding. The hypermetabolic and highly catabolic state of injury is characterized by a diminished level of IGF-1 along with increased levels of stress hormones. Inverse relationships of adiposity and aging on IGF-1 levels are seen both in injured and uninjured subjects. Feeding could restore the IGF-1 levels in non-obese, young patients but it is delayed in obese or elderly subjects. This diminished responsiveness to feeding of IGF-1 hormone deficiency in obese and elderly subjects should be taken into consideration in their post-trauma treatment and may warrant adjuvant administration in these types of patients.

Acute IGF-1 deficiency in multiple trauma victims. Publishing Authors By Initials

M Jeevanandam,NJ Holaday,RF Shamos,SR Petersen,

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Acute IGF-1 deficiency in multiple trauma victims. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Clinical nutrition (Edinburgh, Scotland)

VOLUME: 11

Page Numbers: 352-7

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ISSN: 0261-5614

DAY: 14

MONTH: Dec

YEAR: 1992

Acute IGF-1 deficiency in multiple trauma victims. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Acute IGF-1 deficiency in multiple trauma victims.

AFFILIATION: Trauma Center, St. Joseph's Hospital and Medical Center, 350 West Thomas Road, Phoenix, Arizona, 85013, USA.

Country: England

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MEDLINETA: Clin Nutr

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