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Acute effects of hydroxyethylrutosides on capillary filtration in normal volunteers, patients with venous hypertension and in patients with diabetic microangiopathy (a dose comparison study).

Acute effects of hydroxyethylrutosides on capillary filtration in normal volunteers, patients with venous hypertension and in patients with diabetic microangiopathy (a dose comparison study). Research Abstract Details 

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  • Acute effects of hydroxyethylrutosides on capillary filtration in normal volunteers, patients with venous hypertension and in patients with diabetic microangiopathy (a dose comparison study). Abstract Text:

    m r cesaroneM R Cesarone,g lauroraG Laurora,a ricciA Ricci,g belcaroG Belcaro,p pomanteP Pomante,c candianiC Candiani,m leonM Leon,a n nicolaidesA N Nicolaides,

    The acute effects of hydroxyethylrutosides on capillary filtration were studied in 12 normal subjects, 25 patients with venous hypertension and 22 diabetics with microangiopathy. The two groups of patients randomly received a single oral dose (500 or 1000 mg) of hydroxyethylrutosides. A single dose of 500 mg was used for normal volunteers. In the following 6 hours capillary filtration was studied with straingauge plethysmography. The decrease in capillary filtration was evident within the first hour and was at its peak between the second and fourth hour. After 6 hours it was still significantly below baseline values in patients. The 1000 mg dose was significantly more effective in both groups of patients. This study confirms the efficacy of hydroxyethylrutosides in decreasing capillary filtration. It suggests that the effect of one dose lasts at least 6 hours and also that the higher dose is more effective.

    Acute effects of hydroxyethylrutosides on capillary filtration in normal volunteers, patients with venous hypertension and in patients with diabetic microangiopathy (a dose comparison study). Publishing Authors By Initials

    mr cesaroneMR Cesarone,g lauroraG Laurora,a ricciA Ricci,g belcaroG Belcaro,p pomanteP Pomante,c candianiC Candiani,m leonM Leon,an nicolaidesAN Nicolaides,

    For similar cardiovascular diseases: vascular diseases: venous insufficiency research abstracts see: cardiovascular diseases: vascular diseases: venous insufficiency research

    PUBMED ID PMID:

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    Acute effects of hydroxyethylrutosides on capillary filtration in normal volunteers, patients with venous hypertension and in patients with diabetic microangiopathy (a dose comparison study). Journal Published:

    PUBLICATION TYPE: Randomized Controlled Trial

    Journal: VASA. Zeitschrift für Gefässkrankheiten. Journal f

    VOLUME: 21

    Page Numbers: 76-80

    Journal Abbreviation: VASA

    ISSN: 0301-1526

    DAY: 13

    MONTH: 02

    YEAR: 1992

    Acute effects of hydroxyethylrutosides on capillary filtration in normal volunteers, patients with venous hypertension and in patients with diabetic microangiopathy (a dose comparison study). Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 317051

    Acute effects of hydroxyethylrutosides on capillary filtration in normal volunteers, patients with venous hypertension and in patients with diabetic microangiopathy (a dose comparison study). Keywords Mesh Terms:

    KEYWORDS: Venous Insufficiency

    MESH TERMS: physiopathology

    Chemical & Substance for Abstract: Acute effects of hydroxyethylrutosides on capillary filtration in normal volunteers, patients with venous hypertension and in patients with diabetic microangiopathy (a dose comparison study). Information

    Substance Name: Oxygen

    Registry Number: 7782-44-7

    Grant and Affiliation Information for Acute effects of hydroxyethylrutosides on capillary filtration in normal volunteers, patients with venous hypertension and in patients with diabetic microangiopathy (a dose comparison study).

    AFFILIATION: Microcirculation Laboratory, G. D'Annunzio University, Chieti, Italy.

    Country: SWITZERLAND

    SWITZERLAND Research PublicationSWITZERLAND Research Publication

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    MEDLINETA: Vasa

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