Active immunization of boars against gonadotrop in releasing hormone. I. Effects on reproductive parameters.

Active immunization of boars against gonadotrop in releasing hormone. I. Effects on reproductive parameters. Research Abstract Details 

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Active immunization of boars against gonadotrop in releasing hormone. I. Effects on reproductive parameters. Abstract Text:

T B Grizzle,K L Esbenshade,B H Johnson,

Sexually mature boars were actively immunized against gonadotropin releasing hormone (GnRH) to characterize endocrine and gametogenic changes associated with immunoneutralization of endogenous GnRH. Injections of GnRH conjugated to bovine serum albumin (BSA) given five times over 24 wk induced production of antibodies against GnRH in all animals (n = 5). Active immunization against GnRH reduced serum concentrations of testosterone (P < 0.05) and luteinizing hormone (LH) (P < 0.05), testes volume (P < 0.01), paired testis weights (P < 0.05), paired epididymis weights (P < 0.05), sperm per testis (P < 0.01) and seminiferous tubule diameters (P < 0.001) when compared with controls (n = 4). These results indicate that both steroidogenic and spermatogenic functions are impaired in testes of mature boars actively immunized against GnRH.

Active immunization of boars against gonadotrop in releasing hormone. I. Effects on reproductive parameters. Publishing Authors By Initials

TB Grizzle,KL Esbenshade,BH Johnson,

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Active immunization of boars against gonadotrop in releasing hormone. I. Effects on reproductive parameters. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Theriogenology

VOLUME: 27

Page Numbers: 571-80

Journal Abbreviation: Theriogenology

ISSN: 0093-691X

DAY: 26

MONTH: Apr

YEAR: 1987

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LANGUAGE: eng

NlmUniqueID: 421510

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Grant and Affiliation Information for Active immunization of boars against gonadotrop in releasing hormone. I. Effects on reproductive parameters.

AFFILIATION: Department of Animal Science North Carolina State University Raleigh, NC 27695-7621 USA.

Country: United States

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MEDLINETA: Theriogenology

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