Activation of the trigeminovascular system by mechanical distension of the superior sagittal sinus in the cat.

Activation of the trigeminovascular system by mechanical distension of the superior sagittal sinus in the cat. Research Abstract Details 

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Activation of the trigeminovascular system by mechanical distension of the superior sagittal sinus in the cat. Abstract Text:

M A Moskowitz,

Distension of dural sinuses in man produces migraine-like pain. In eight alpha-chloralose anaesthetized cats mechanical distension of the superior sagittal sinus with a small intraluminal device was used to activate single units in the dorsolateral C2 spinal cord. Units in this region have been shown to respond to electrical stimulation of the superior sagittal sinus in the cat model. Linked responses to mechanical dilatation could only be obtained with very rapid stretching stimuli or high amplitudes of distension of the vessel. Lower thresholds for transduction of distension in the vessel wall may depend on transferral to the dura or biochemical or neural pre-sensitization of the superior sagittal sinus. These data are consistent with the view that migraine is not primarily a vascular disorder but requires at least humoral or neural facilitation.

Activation of the trigeminovascular system by mechanical distension of the superior sagittal sinus in the cat. Publishing Authors By Initials

MA Moskowitz,

For similar nervous system: peripheral nervous system: peripheral nerves: cranial nerves: trigeminal nerve research abstracts see: nervous system: peripheral nervous system: peripheral nerves: cranial nerves: trigeminal nerve research

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Activation of the trigeminovascular system by mechanical distension of the superior sagittal sinus in the cat. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Cephalalgia : an international journal of headache

VOLUME: 12

Page Numbers: 133-6

Journal Abbreviation: Cephalalgia

ISSN: 0333-1024

DAY: 11

MONTH: Jun

YEAR: 1992

Activation of the trigeminovascular system by mechanical distension of the superior sagittal sinus in the cat. Information

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LANGUAGE: eng

NlmUniqueID: 8200710

Activation of the trigeminovascular system by mechanical distension of the superior sagittal sinus in the cat. Keywords Mesh Terms:

KEYWORDS: Trigeminal Nerve

MESH TERMS: physiopathology

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Grant and Affiliation Information for Activation of the trigeminovascular system by mechanical distension of the superior sagittal sinus in the cat.

AFFILIATION: Department of Neurology, Prince Henry Hospital, Sydney, Australia.

Country: NORWAY

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MEDLINETA: Cephalalgia

REFSOURCE: Cephalalgia. 1992 Jun;12(3):127

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