Activation of neural stem and progenitor cells after brain injury.

Activation of neural stem and progenitor cells after brain injury. Research Abstract Details 

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Activation of neural stem and progenitor cells after brain injury. Abstract Text:

Darry K Miles,Steven G Kernie,

Neural stem and progenitor cells in the mammalian brain persist and are functional well into adulthood. Reservoirs for these cells are found in both the subventricular zone and the dentate gyrus of the hippocampus. It is still unclear what role these cells may play in humans during normal brain maturation. In addition, there is currently tremendous speculation regarding the potential role of these cells in providing a substrate for recovery and repair after injury. This review provides an overview of the existing data regarding how neural stem and progenitor cells respond to various types of brain injury. In particular, we focus upon their role in the dentate gyrus since this brain area provides a compelling and tractable model of how the brain may use its ability for endogenous regeneration to recover from a variety of injuries.

Activation of neural stem and progenitor cells after brain injury. Publishing Authors By Initials

DK Miles,SG Kernie,

For similar cells: stem cells research abstracts see: cells: stem cells research

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Activation of neural stem and progenitor cells after brain injury. Journal Published:

PUBLICATION TYPE: Review

Journal: Progress in brain research

VOLUME: 157

Page Numbers: 187-197

Journal Abbreviation: Prog. Brain Res.

ISSN: 0079-6123

DAY: 3

MONTH: 12

YEAR: 2006

Activation of neural stem and progenitor cells after brain injury. Information

Number of References: 108

LANGUAGE: eng

NlmUniqueID: 376441

Activation of neural stem and progenitor cells after brain injury. Keywords Mesh Terms:

KEYWORDS: Stem Cells

MESH TERMS: physiology

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Grant and Affiliation Information for Activation of neural stem and progenitor cells after brain injury.

AFFILIATION: Department of Pediatrics and Center for Developmental Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Country: Netherlands

AGENCY: United States NICHD

GRANT: 1K08 HD 01470-01

ACRONYM: HD

MEDLINETA: Prog Brain Res

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