Acquired immunodeficiency syndrome-associated psoriasis and Reiter's syndrome.

Acquired immunodeficiency syndrome-associated psoriasis and Reiter's syndrome. Research Abstract Details 

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Acquired immunodeficiency syndrome-associated psoriasis and Reiter's syndrome. Abstract Text:

Human immunodeficiency virus (HIV) causes a spectrum of immunodysfunction, the most severe of which is the acquired immunodeficiency syndrome (AIDS). We have followed the course of psoriasis in 13 patients over 2 1/2 years in a population of more than 1000 HIV-positive individuals. Four patients had a history of mild psoriasis that became severe and uncontrollable as symptoms of immunodeficiency developed. Psoriasis and HIV positivity, AIDS-related complex, or AIDS simultaneously developed in nine patients. In addition to psoriasis, Reiter's syndrome (arthritis, urethritis, and conjunctivitis) developed in one patient in the first group and three patients in the second group. Opportunistic infections, especially candidiasis and Staphylococcus, drugs, and an altered immune system may contribute to the development or flare of psoriasis in these patients. The appearance of severe psoriasis (especially in a patient with other risk factors for HIV) should prompt evaluation for HIV, and may be a poor prognostic indicator in HIV-positive patients, since nine of our 13 patients have died. Immunosuppressive therapy with methotrexate is contraindicated in this group of patients. Newer forms of drug therapy including etretinate show promising results for the management of AIDS-associated psoriasis.

Acquired immunodeficiency syndrome-associated psoriasis and Reiter's syndrome. Publishing Authors By Initials

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Acquired immunodeficiency syndrome-associated psoriasis and Reiter's syndrome. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Archives of dermatology

VOLUME: 123

Page Numbers: 1622-32

Journal Abbreviation: Arch Dermatol

ISSN: 0003-987X

DAY: 17

MONTH: Dec

YEAR: 1987

Acquired immunodeficiency syndrome-associated psoriasis and Reiter's syndrome. Information

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LANGUAGE: eng

NlmUniqueID: 372433

Acquired immunodeficiency syndrome-associated psoriasis and Reiter's syndrome. Keywords Mesh Terms:

KEYWORDS: Skin

MESH TERMS: pathology

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Grant and Affiliation Information for Acquired immunodeficiency syndrome-associated psoriasis and Reiter's syndrome.

AFFILIATION: Department of Dermatology, University of Texas Health Sciences Center, Houston.

Country: UNITED STATES

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MEDLINETA: Arch Dermatol

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