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Acetohydroxamate in struvite stones: in vivo study.

Acetohydroxamate in struvite stones: in vivo study. Research Abstract Details 

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  • Acetohydroxamate in struvite stones: in vivo study. Abstract Text:

    a aroldiA Aroldi,g grazianiG Graziani,c castelnovoC Castelnovo,g colussiG Colussi,m surianM Surian,a mandressiA Mandressi,e mascheroniE Mascheroni,i pazardjiklianI Pazardjiklian,a paganoA Pagano,c ponticelliC Ponticelli,

    This report describes the results obtained with a combination of acetohydroxamic acid (AHA) and antibacterial agents in 13 patients with recurrent struvite stones complicated by refractory infections with urease-producing bacteria. Intravenous antibiotic pulses plus oral AHA achieved urine sterilisation in all. Then oral chemotherapy plus AHA was given for a mean period of 10.8 +/- 5.4 months. In four patients, the urine remained sterile, but in all the patients urinary pH remained below 6.4 and urinary NH4+ below 40 mg/dl. Despite the persistence of urea-splitting bacteria, the radiographic data showed an arrest of stone growth during the first year of treatment.

    Acetohydroxamate in struvite stones: in vivo study. Publishing Authors By Initials

    a aroldiA Aroldi,g grazianiG Graziani,c castelnovoC Castelnovo,g colussiG Colussi,m surianM Surian,a mandressiA Mandressi,e mascheroniE Mascheroni,i pazardjiklianI Pazardjiklian,a paganoA Pagano,c ponticelliC Ponticelli,

    For similar bacterial infections and mycoses: infection: urinary tract infections research abstracts see: bacterial infections and mycoses: infection: urinary tract infections research

    PUBMED ID PMID:

    MEDLINE DATE:

    Acetohydroxamate in struvite stones: in vivo study. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Proceedings of the European Dialysis and Transplan

    VOLUME: 20

    Page Numbers: 469-72

    Journal Abbreviation:

    ISSN: 0071-2736

    DAY: 21

    MONTH: 02

    YEAR: 1983

    Acetohydroxamate in struvite stones: in vivo study. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 355210

    Acetohydroxamate in struvite stones: in vivo study. Keywords Mesh Terms:

    KEYWORDS: Urinary Tract Infections

    MESH TERMS: drug therapy

    Chemical & Substance for Abstract: Acetohydroxamate in struvite stones: in vivo study. Information

    Substance Name: Urease

    Registry Number: EC 3.5.1.5

    Grant and Affiliation Information for Acetohydroxamate in struvite stones: in vivo study.

    AFFILIATION:

    Country: ENGLAND

    ENGLAND Research PublicationENGLAND Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Proc Eur Dial Transplant Assoc

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

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