Accuracy of plasma turbidity measurement for determining fat intolerance during total parenteral nutrition.

Accuracy of plasma turbidity measurement for determining fat intolerance during total parenteral nutrition. Research Abstract Details 

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Accuracy of plasma turbidity measurement for determining fat intolerance during total parenteral nutrition. Abstract Text:

J ,A ,M Lindholm,

The accuracy of plasma turbidity measurements in predicting ability to metabolise intravenous fat emulsions during total parenteral nutrition was studied in 35 adult surgical patients. Plasma turbidity, expressed as a light scattering index (LSI), was determined by nephelometry and compared with measured triglyceride (TG) concentrations. A poor coefficient of correlation was found between LSI and TG (r = 0.52). The sensitivity and specificity of LSI in predicting TG concentration were 19% and 96% respectively. This indicates that the measurement of LSI is more useful in ruling out hypertriglyceridaemia than in detecting it. Consequently, clinical tolerance of intravenous fat emulsion cannot be monitored by measuring plasma turbidity. In order to avoid metabolic complications which may occasionally occur during intravenous nutritional therapy including fat emulsion, determination of plasma TG levels at timed intervals are recommended.

Accuracy of plasma turbidity measurement for determining fat intolerance during total parenteral nutrition. Publishing Authors By Initials

J ,A ,M Lindholm,

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Accuracy of plasma turbidity measurement for determining fat intolerance during total parenteral nutrition. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Clinical nutrition (Edinburgh, Scotland)

VOLUME: 9

Page Numbers: 172-5

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ISSN: 0261-5614

DAY: 13

MONTH: Jun

YEAR: 1990

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LANGUAGE: eng

NlmUniqueID: 8309603

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Grant and Affiliation Information for Accuracy of plasma turbidity measurement for determining fat intolerance during total parenteral nutrition.

AFFILIATION: Department of Surgery, Huddinge University Hospital, S-141 86 Huddinge, Sweden.

Country: England

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MEDLINETA: Clin Nutr

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