Accumulation of health disorders as a systemic measure of aging: Findings from the NLTCS data.

Accumulation of health disorders as a systemic measure of aging: Findings from the NLTCS data. Research Abstract Details 

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Accumulation of health disorders as a systemic measure of aging: Findings from the NLTCS data. Abstract Text:

Alexander Kulminski,Anatoli Yashin,Svetlana Ukraintseva,Igor Akushevich,Konstantin Arbeev,Kenneth Land,Kenneth Manton,

BACKGROUND: An index of age-associated health/well-being disorders (deficits), called the "frailty index" (FI), appears to be a promising characteristic to capture dynamic variability in aging manifestations among age-peers. In this study we provide further support toward this view focusing on the analysis of the FI age patterns in the participants of the National Long Term Care Survey (NLTCS). METHODS: The NLTCS assessed health and functioning of the U.S. elderly in 1982, 1984, 1989, 1994, and 1999. Detailed information for our sample was assessed from about 26,700 interviews. The individual FI is defined as a proportion of health deficits for a given person. RESULTS: The FI in the NLTCS exhibits accelerated age patterns. The acceleration is larger for elderly who, at younger ages, had a lower FI (low FI group) than for those who showed a higher FI at younger ages (high FI group). Age-patterns for low and high FI groups tend to converge at advanced ages. The rate of deficit accumulation is sex-sensitive. CONCLUSIONS: The accelerated FI age patterns suggest that FI can be considered as a systemic measure of aging process. Convergence of the (sex-specific) FI age patterns for low and high FI groups by extreme ages might reflect the limit of the FI-specific (or systemic) age as well as the limit of adaptation capacity in aging individuals.

Accumulation of health disorders as a systemic measure of aging: Findings from the NLTCS data. Publishing Authors By Initials

A Kulminski,A Yashin,S Ukraintseva,I Akushevich,K Arbeev,K Land,K Manton,

For similar reproductive and urinary physiology: reproduction: sex characteristics research abstracts see: reproductive and urinary physiology: reproduction: sex characteristics research

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Accumulation of health disorders as a systemic measure of aging: Findings from the NLTCS data. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Mechanisms of ageing and development

VOLUME: 127

Page Numbers: 840-8

Journal Abbreviation: Mech. Ageing Dev.

ISSN: 0047-6374

DAY: 14

MONTH: 09

YEAR: 2006

Accumulation of health disorders as a systemic measure of aging: Findings from the NLTCS data. Information

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LANGUAGE: eng

NlmUniqueID: 347227

Accumulation of health disorders as a systemic measure of aging: Findings from the NLTCS data. Keywords Mesh Terms:

KEYWORDS: Sex Characteristics

MESH TERMS: statistics & numerical data

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Grant and Affiliation Information for Accumulation of health disorders as a systemic measure of aging: Findings from the NLTCS data.

AFFILIATION: Center for Demographic Studies, Duke University, 2117 Campus Drive, Box 90408, Durham, NC 27708, USA. Alexander.Kulminski@duke.edu

Country: Ireland

AGENCY: United States NIA

GRANT: R01AG028259-02

ACRONYM: AG

MEDLINETA: Mech Ageing Dev

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