Accommodation of grafts: implications for health and disease.

Accommodation of grafts: implications for health and disease. Research Abstract Details 

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Accommodation of grafts: implications for health and disease. Abstract Text:

Amy H Tang,Jeffrey L Platt,

Accommodation refers to the acquired resistance of a graft to immune-mediated injury. It is typically observed after antibodies that would cause rejection of a graft are removed from a recipient and then later return. In addition to being induced in this manner, accommodation can occur spontaneously, without depleting antibodies. Indeed, we postulate spontaneous accommodation may be the most common outcome of clinical organ transplantation. The paper reviews the current understanding of accommodation, emphasizing recent advances and important questions. Among the recent advances are the discoveries of potentially broader relevance of accommodation for biology and immunology and pathways by which accommodation may be achieved. To investigate these pathways and to understand how accommodation begins and how it evolves, clinical organ transplants might offer a useful and incisive model.

Accommodation of grafts: implications for health and disease. Publishing Authors By Initials

AH Tang,JL Platt,

For similar surgical procedures, operative: transplantation: transplantation, homologous research abstracts see: surgical procedures, operative: transplantation: transplantation, homologous research

PUBMED ID PMID:

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Accommodation of grafts: implications for health and disease. Journal Published:

PUBLICATION TYPE: Review

Journal: Human immunology

VOLUME: 68

Page Numbers: 645-51

Journal Abbreviation: Hum. Immunol.

ISSN: 0198-8859

DAY: 15

MONTH: 05

YEAR: 2007

Accommodation of grafts: implications for health and disease. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8010936

Accommodation of grafts: implications for health and disease. Keywords Mesh Terms:

KEYWORDS: Transplantation, Homologous

MESH TERMS: immunology

Chemical & Substance for Abstract: Accommodation of grafts: implications for health and disease. Information

Substance Name: HLA Antigens

Registry Number: 0

Grant and Affiliation Information for Accommodation of grafts: implications for health and disease.

AFFILIATION: Transplantation Biology, Mayo Clinic College of Medicine, Rochester, MN, USA.

Country: United States

AGENCY: United States NHLBI

GRANT: HL52297

ACRONYM: HL

MEDLINETA: Hum Immunol

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