Acceleration of cerebral ventricular expansion in the Cardiovascular Health Study.

Acceleration of cerebral ventricular expansion in the Cardiovascular Health Study. Research Abstract Details 

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Acceleration of cerebral ventricular expansion in the Cardiovascular Health Study. Abstract Text:

Owen T Carmichael,L H Kuller,O L Lopez,P M Thompson,R A Dutton,A Lu,S E Lee,J Y Lee,H J Aizenstein,C C Meltzer,Y Liu,A W Toga,J T Becker,

Interactions between prevalent late-life medical conditions and expansion of the cerebral ventricles are not well understood. Thirty elderly subjects received three magnetic resonance (MR) scans each, in 1997-1999, 2002-2004, and 2003-2005. A linear expansion model of MR-measured lateral ventricle volume was estimated for each subject by fitting a line to a plot of their 1997-1999 and 2002-2004 volumes as a function of time. Acceleration in ventricular expansion was defined as the deviation between the 2003-2005 volumes measured from MR and the 2003-2005 volumes predicted by the linear expansion model. Ventricular acceleration was analyzed in a multivariate model with age, race, history of heart disease, diabetes, and hypertension as fixed effects. Ventricular acceleration was significantly higher in non-whites, diabetics, and those without heart disease (p<0.05). Ventricular acceleration was higher in subjects with a history of hypertension, but the difference was not statistically significant (p=0.08). Acceleration of ventricular expansion in the elderly may be related to demographic and cardiovascular factors.

Acceleration of cerebral ventricular expansion in the Cardiovascular Health Study. Publishing Authors By Initials

OT Carmichael,LH Kuller,OL Lopez,PM Thompson,RA Dutton,A Lu,SE Lee,JY Lee,HJ Aizenstein,CC Meltzer,Y Liu,AW Toga,JT Becker,

For similar natural sciences: time: time factors research abstracts see: natural sciences: time: time factors research

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Acceleration of cerebral ventricular expansion in the Cardiovascular Health Study. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Neurobiology of aging

VOLUME: 28

Page Numbers: 1316-21

Journal Abbreviation: Neurobiol. Aging

ISSN: 1558-1497

DAY: 27

MONTH: 07

YEAR: 2006

Acceleration of cerebral ventricular expansion in the Cardiovascular Health Study. Information

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LANGUAGE: eng

NlmUniqueID: 8100437

Acceleration of cerebral ventricular expansion in the Cardiovascular Health Study. Keywords Mesh Terms:

KEYWORDS: Time Factors

MESH TERMS: anatomy & histology

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Grant and Affiliation Information for Acceleration of cerebral ventricular expansion in the Cardiovascular Health Study.

AFFILIATION: Neurology Department, University of California, Center For Neuroscience, 1544 Newton Court, Davis, CA 95616, United States. ocarmichael@ucdavis.edu <ocarmichael@ucdavis.edu>

Country: United States

AGENCY: United States NHLBI

GRANT: U01 HL080295

ACRONYM: HL

MEDLINETA: Neurobiol Aging

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