Absorption and secretion of fluid and electrolytes by the rectum.

Absorption and secretion of fluid and electrolytes by the rectum. Research Abstract Details 

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Absorption and secretion of fluid and electrolytes by the rectum. Abstract Text:

C J Edmonds,

Although the amounts of ions and water absorbed and secreted by the rectum are small compared to those of other parts of the colon, rectal epithelium is capable of generating and maintaining considerable ionic gradients. Absorption of Na+ and Cl- and secretion of K+ and HCO-3 leads to relatively low concentrations of the former and high concentrations of the latter within the lumen. Detailed examination of the transport processes indicates that the epithelial mechanisms can be interpreted in terms of ionic movements through transcellular and paracellular pathways. These results show that the epithelium is relatively tight and largely amiloride-sensitive. Active Na+ absorption and apparent active K+ and HCO-3 secretion occur. The secretion of HCO-3 is related to Cl- and organic anion absorption. Mineralocorticoids increase the transepithelial potential difference (p.d.) as well as stimulating Na+ absorption and K+ secretion. Rectal epithelium may, with various physiological or pathological stimuli, become overtly secretory of a predominantly NaCl containing fluid but it remains uncertain whether some secretion is normally present although masked by absorption.

Absorption and secretion of fluid and electrolytes by the rectum. Publishing Authors By Initials

CJ Edmonds,

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Absorption and secretion of fluid and electrolytes by the rectum. Journal Published:

PUBLICATION TYPE: Review

Journal: Scandinavian journal of gastroenterology. Suppleme

VOLUME: 93

Page Numbers: 79-87

Journal Abbreviation: Scand. J. Gastroenterol. Suppl

ISSN: 0085-5928

DAY: 13

MONTH: 02

YEAR: 1984

Absorption and secretion of fluid and electrolytes by the rectum. Information

Number of References: 55

LANGUAGE: eng

NlmUniqueID: 437034

Absorption and secretion of fluid and electrolytes by the rectum. Keywords Mesh Terms:

KEYWORDS: Water

MESH TERMS: metabolism

Chemical & Substance for Abstract: Absorption and secretion of fluid and electrolytes by the rectum. Information

Substance Name: Chlorine

Registry Number: 7782-50-5

Grant and Affiliation Information for Absorption and secretion of fluid and electrolytes by the rectum.

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Country: NORWAY

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MEDLINETA: Scand J Gastroenterol Suppl

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