In this article, a weighted zero-inflated Poisson (W-ZIP) approach to modelling colorectal adenoma data is used in which the number of recurrent adenomas is subject to measurement error and some participants might have their follow-up colonoscopy conducted before the end of trial. The weights are used to adjust for varying follow-up and obtained from a nonparametric survival function derived from the lengths of follow-up. It is shown that logistic regression (LR) and survival analysis tend to underestimate recurrence rate due to measurement error on the status of recurrence. A simulation study shows that the W-ZIP model is robust to the assumption of the underlying distribution of time-to-recurrence and is less affected by misclassification at follow-up colonoscopy when compared with LR and survival analysis approaches. The method described here is illustrated with an example from a colon cancer study.
A weighted zero-inflated Poisson model for estimation of recurrence of adenomas. Publishing Authors By Initials
A weighted zero-inflated Poisson model for estimation of recurrence of adenomas. Journal Published:
PUBLICATION TYPE: Research Support, Non-U.S. Gov
Journal: Statistical methods in medical research
VOLUME: 16
Page Numbers: 155-66
Journal Abbreviation:
ISSN: 0962-2802
DAY: 3
MONTH: Apr
YEAR: 2007
A weighted zero-inflated Poisson model for estimation of recurrence of adenomas. Information
Number of References:
LANGUAGE: eng
NlmUniqueID: 9212457
A weighted zero-inflated Poisson model for estimation of recurrence of adenomas. Keywords Mesh Terms:
KEYWORDS: United States
MESH TERMS: physiopathology
Chemical & Substance for Abstract: A weighted zero-inflated Poisson model for estimation of recurrence of adenomas. Information
Substance Name:
Registry Number:
Grant and Affiliation Information for A weighted zero-inflated Poisson model for estimation of recurrence of adenomas.
AFFILIATION: Mel and Enid Zuckerman College of Public Health and Arizona Cancer Center, University of Arizona, Tucson 85724-5024, USA. phsu@azcc.arizona.edu
Country: England
AGENCY: United States NCI
GRANT: CA 041108
ACRONYM: CA
MEDLINETA: Stat Methods Med Res
REFSOURCE:
DATABASENAME:
ACCESSION NUMBER:
Number Hits: 0
A weighted zero-inflated Poisson model for estimation of recurrence of adenomas Related Publications